Fighting TB with Open-Source Tech
VideoFighting TB with Open-Source TechJuly 14, 2017EndTB (Expand New Drug markets for Tuberculosis) is a comprehensive international project that aims to find shorter, less toxic, oral-only, and more effective treatments for TB.Read more about how MSF is helping patients get access to new TB drugs.
Vera Marie Kroesen, Paula Rodr íguez-Martínez, Eric García, Yaiza Rosales, Jorge Díaz, Montse Martín-Céspedes, Gustavo Tapia, Maria Rosa Sarrias, Pere-Joan Cardona, Cristina Vilaplana
[East African] Patients with multi-drug resistant tuberculosis (MDR-TB), a more complicated form of the disease, can now heave a sigh of relief after the Ministry of Health formally adopted a new regimen which will reduce treatment time from the current two years to 11 months or less.
Chinese researchers found that digital tomosynthesis with a metal artifact...Read more on AuntMinnie.comRelated Reading: CAD of chest tomosynthesis works best for new readers Digital tomo refines postoperative imaging of hand fractures Digital tomosynthesis works well for spinal tuberculosis DR tomosynthesis gives wrist radiography a hand DR tomo holds promise for fungal pneumonia surveillance
Discussion Normal kidneys regulate water balance to maintain a plasma osmolality of 275-290 mOsm/kg normally. Thirst and arginine vasopressin or antidiuretic hormone (ADH) are the primary regulators of plasma osmolality. ADH is made in the hypothalamus and released by the posterior pituitary gland. ADH acts on the kidney’s distal collecting duct to increase water reabsorption. ADH is appropriately released in hypovolemic states, such as dehydration caused by gastroenteritis. ADH has an ~10 minute half-life and therefore can respond to rapid changes in volume status. Sodium balance is regulated by aldosterone (as part...
In this study, mice were immunized with fusion protein ESAT6-Ag85B-MPT64 (190 –198)-Mtb8.4-Rv2626c (LT70) based subunit vaccine three times according to the following schedules: ① 0, 3rd and 6th week respectively (0-3-6w), ② 0, 4th and 12th week (0-4-12w), and ③ 0, 4th and 24th week (0-4-24w).
This report highlights a rare case of primary TB of gingiva, presenting as severe gingival overgrowth in a patient with 4th month of pregnancy. This case strongly suggests the importance of suspecting TB as the differential diagnosis of gingival overgrowth and therefore, playing a critical role in the early detection and treatment. Interdisciplinary collaboration for diagnosis and management resulted in the successful outcome and prevented the obstetric complications in this case.
Microbial Drug Resistance, Ahead of Print.
It is very nice to see the reprint version of our paper titled “clinical and pathological analyses of tuberculosis in the oral cavity: report of 11 cases” published in Oral Surgery Oral Medicine Oral Pathology Oral Radiology (2018;125: 44-51). Unfortunately, an important statement of “Wu-tong Ju and Yong Fu contributed equally to this paper” is missing in the reprint version, which was presented in our manuscript and the proof. Although the sequence of author list is correct, the statement should be added in the reprint version of paper because Yong Fu and Wu-tong Ju contributed equally to this paper.
atarzyna Gobis Compounds possessing benzimidazole system exhibit significant antituberculous activity. In order to examine how structure modifications affect tuberculostatic activity, a series of benzazole derivatives were synthesized and screened for their antitubercular activity. The compounds 1–20 were obtained by the reaction between o-diamine, o-aminophenol, or o-aminothiophenol with carboxylic acids or thioamides. The newly synthesized compounds were characterized by IR, 1H-NMR, 13C-NMR spectra, and elemental analysis. Synthesized benzazoles were evaluated for their tuberculostatic activity toward Mycobacte...
CONCLUSIONS: Specialists had diverse perceptions and clinical practices regarding severe asthma and ACOS patients. This heterogeneity must be considered in future studies and strategy development for severe asthma and ACOS. PMID: 29676069 [PubMed]