Immunosuppressive Treatment in C3 Glomerulopathy: Is it Really Effective?

CONCLUSION: Although patients receiving immunosuppressive treatments had higher proteinuria and lower serum albumin at baseline, there were no differences between these patients and those receiving conservative care alone in proteinuria remission or in the decline of renal function. Younger age, higher proteinuria, lower eGFR, and the presence of crescentic and sclerotic glomeruli, severity of interstitial fibrosis, and no remission of proteinuria predicted the progression of kidney disease.
PMID: 28700996 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - July 13, 2017 Category: Urology & Nephrology Authors: Caliskan Y, Torun ES, Tiryaki TO, Oruc A, Ozluk Y, Akgul SU, Temurhan S, Oztop N, Kilicaslan I, Sever MS Tags: Am J Nephrol Source Type: research