PodMed – Week of July 17, 2017

This week’s topics include diet quality and longevity, health and coffee, treating depression, and prostatectomy in early prostate cancer. Program notes: 0:33 Coffee drinking and longevity 1:33 Over 185,000 people followed in one study 2:32 Can’t advocate for a type of coffee 3:01 Prostatectomy or not in early prostate cancer 4:01 Higher incidence of side […]
Source: Johns Hopkins Medicine Weekly Health News - Category: Consumer Health News Authors: Tags: All Podcasts Death and Dying Diet Mental health PodMed Prevention Source Type: podcasts

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ConclusionsThis study supports previous findings that higher performance status, cancer diagnosis and higher baseline pain intensity predict analgesic RT response. The study presents new data showing that presence of soft tissue expansion predicts RT response and that CRP is not significantly associated with analgesic RT response.Clinical trial identificationNCT02107664 (Date of registration April 8, 2014).Legal entity responsible for the studyP ål Klepstad.FundingThe European Palliative Care Research Centre (PRC).DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
iérrez A, Rubio-Briones J, Cauli O Abstract OBJECTIVE: To evaluate the role of peripheral inflammation (leukocyte differential count, the proinflammatory cytokines IL-beta, TNF-α, IL-6, IL-8, and the inflammatory markers fibrinogen and C-reactive protein [CRP]) in frailty syndrome in patients with prostate cancer (CaP) undergoing antiandrogen therapy (ADT). METHODS: A total of 46 men between 51 and 92 years of age with CaP and receiving ADT were classified as frail, prefrail or robust according to the Fried scale. A geriatric assessment was performed, based on the Minimental State Examination for...
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
ConclusionsConsistent with previous large-scale meta-analyses and reviews, results supported the causal role of higher BMI in increasing the risk of several common causes of death, including cancers with increasing global incidence. We also found positive effects of BMI on mortality from respiratory disease, prostate cancer, and lung cancer, which has been inconsistently reported in the literature, suggesting that the causal role of higher BMI in mortality from these diseases may be underestimated. Furthermore, we expect different patterns of bias in the current observational and IV analyses; therefore, the similarities be...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
AbstractPurposeThis  study aimed to investigate the prevalence of sleeping problems in prostate cancer survivors and to explore the role of predisposing, precipitating and perpetuating factors in this process.MethodsUsing a cross-sectional design, 3348 prostate cancer survivors between 2 and 18  years post diagnosis reported experiences of insomnia using the QLQC30, along with their sociodemographic characteristics, health status and treatment(s) received. The EQ5D-5L and QLQPR25 assessed survivors’ overall and prostate cancer–specific health-related quality of life. A hierarchical mu ltiple regressio...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Astudy published this week inDepression&Anxiety suggests that among patients with cancer who are prescribed antidepressants, those who take the medication may live longer than those who are nonadherent.Patients with cancer are known to have higher rates of depression than the general public —a factor that may reduce adherence to cancer treatment and increase their risk of death. The findings “add to the pressing need to encourage adherence to [antidepressants] among cancer patients,” wrote Gal Shoval, M.D., of the Geha Mental Health Center in Tel Aviv, Israel, and colleagues.To examine the relationshi...
Source: Psychiatr News - Category: Psychiatry Tags: antidepressants anxiety cancer depression & Gal Shoval medication adherence survival Source Type: research
Authors: Plitzko L, Mehnert-Theuerkauf A, Götze H Abstract INTRODUCTION: Resilience is considered as a resource in coping with psychological distress and traumatic experiences and plays an increasing role in psycho-oncology research. The aim of the study is to analyse the resilience in long-term cancer survivors depending on depression, anxiety, sociodemographic and disease-related factors and to compare with the general population. MATERIAL AND METHODS: Our study includes data from 972 patients (53% male, mean age=67 years, 25% prostate cancer, 22% breast cancer) 5 or 10 years after cancer diagnosis via t...
Source: PPmP Psychotherapie Psychosomatik Medizinische Psychologie - Category: Psychiatry & Psychology Tags: Psychother Psychosom Med Psychol Source Type: research
ConclusionsThere was no difference in the patient ’s QOL, except that CAB group was associated with significantly better pain relief than LHRH agonist monotherapy at 3 months following ADT, which was not sustained thereafter. Our results suggest that the benefit of prolonged (≥ 3 months) CAB is questionable in terms of patients’ QOL.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Conclusion: It was shown that radical prostatectomy causes impairment in the quality of life of men, requiring care from health professionals to minimize the effects of the most common complications. Educational interventions and multi-professional support based on a better understanding of the physical and psychosocial implications are recommended to help improve the quality of life of men after radical prostatectomy.
Source: Acta Paulista de Enfermagem - Category: Nursing Source Type: research
ConclusionsThese results suggest that vortioxetine may be useful in mitigating cognitive impairment associated with ADT for prostate cancer.
Source: Psychopharmacology - Category: Psychiatry Source Type: research
ConclusionProstate cancer survivors experience barriers when in need of depression care.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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