Novartis stocks drug cabinet with "Big-3" arthritis blockbusters
ZURICH (Reuters) - Switzerland's Novartis is stocking up cheaper versions of the world's top-selling arthritis medicines, hoping a broad portfolio gives it an edge on rivals with narrower offerings.
Authors: Serio I, Tovoli F Abstract Rheumatoid arthritis (RA) is an immune-mediated condition which primarily affects the joints, but with critical extra-articular manifestations, including a significantly increased cardiovascular risk. Patients suffering from RA can develop deforming and disabling alterations of the affected joints. Their quality of life can be substantially affected, and their life expectancy is shorter compared to that of healthy subjects. Fortunately, several pathogenic mechanisms characterizing RA have been identified, leading to the development of targeted drugs. Inhibitors of tumor necrosis ...
(MedPage Today) -- EULAR task force promotes patient-centered framework, personalized management
CONCLUSIONS: Decisions on what method to use should be based on considerations of the route of medication administration, the resources available, setting and aim of the assessment. Combining different methods may provide wider insights into adherence and persistence, including patient behaviour. PMID: 29770718 [PubMed - as supplied by publisher]
Authors: Gautam RK, Sharma S, Sharma K, Gupta G Abstract Available conventional drugs produce several side effects; thus, a potent herbal drug is urgently required for the management of rheumatoid arthritis. The present investigation was performed to evaluate the antiarthritic activity of butanol fraction of Punica granatum Linn. rind methanolic extract (PGBF) against Freund's complete adjuvant (FCA)-induced arthritis in rats. An acute toxicity study of butanol fraction was conducted, accompanied by a study of its antiarthritic activity. Chromatography (thin layer chromatography and high-performance thin layer chro...
CONCLUSION: T cell subtypes and potential T cell function are altered in pediatric patients with uveitis and arthritis as compared to healthy children. PMID: 29771573 [PubMed - as supplied by publisher]
The aim of this systematic review was to inform the update of European League Against Rheumatism (EULAR) Recommendations for the management of Beh çet's syndrome (BS), on the evidence for the treatment of skin, mucosa and joint involvement of BS.
Conclusion Our assay can quantify both sub-therapeutic and therapeutic concentrations of bioavailable adalimumab in patient serum samples. This assay design provides an alternative to isotope-labeled peptides approach currently adopted in targeted proteomics methods.
Conclusions Consent remains challenging even with a standardized process. Information retention improves significantly with the use of information sheets. We advocate the use of standard consent and provision of patient information sheets for commonly performed procedures.
Rheumatoid arthritis is a chronic disorder affecting the joints. Some essential oils may help to reduce the major symptoms, such as pain, inflammation, and swelling. In this article, we explore current evidence that supports the use of seven essential oils, how to use them, and which carrier oils are best.
Bill St.Clair, MD, MACR, says one of the most exciting and proudest moments in his life wasn’t earning his medial degree or seeing his first published article on arthritis and rheumatology. Not even close. It was the 1991 National Collegiate Athletic Association (NCAA) basketball semifinal. Specifically, the basketball game between Duke University and the University... [Read More]