Is controlled drinking a reasonable therapy target for alcohol dependence? For.

[Is controlled drinking a reasonable therapy target for alcohol dependence? For.] Nervenarzt. 2014 Jun 19; Authors: Zimmermann US PMID: 24939081 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - Category: Neurology Authors: Tags: Nervenarzt Source Type: research

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Publication date: Available online 23 August 2019Source: The Social Science JournalAuthor(s): Zefeng BaiAbstractThe present study investigates the impact of two drinking habits – moderate drinking and heavy drinking – on marijuana use among college-aged youths. Utilizing data from the National Longitudinal Survey of Youth 97 (NLSY97), this paper reveals that there is a positive association between both drinking habits and marijuana use in the long run, indicating that alcohol and marijuana are complements. However, in the short run, the association between marijuana and alcohol varies based on different drinkin...
Source: The Social Science Journal - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 22 August 2019Source: International Journal of PharmaceuticsAuthor(s): Rosa S. Sequeira, Sónia P. Miguel, Cátia S.D. Cabral, André F. Moreira, Paula Ferreira, Ilídio J. CorreiaAbstractNanofiber-based wound dressings are currently being explored as delivery systems of different biomolecules for avoiding skin infections as well as improve/accelerate the healing process. In the present work, a nanofibrous membrane composed of poly(vinyl alcohol) (PVA) and lysine (Lys) was produced by using the electrospinning technique. Further, anti-inflammatory (ibuprofen (IBP))...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
This study aims to explore the effects of GP extracts on alleviating non-alcoholic fatty liver disease (NAFLD). In this experiment, C57BL/6 J mice were randomly assigned into normal diet control (ND), HFHC (high-fat and high-cholesterol) and HFHC + GP (GP) groups. Mice in HFHC group were fed HFHC diet combined with fructose drinking water for 12 weeks to induce the animal model of NAFLD, followed by ordinary drinking water until the end of the experiment. In the HFHC + GP group, mice were fed HFHC diet combined with fructose drinking water for 12 weeks, followed by GP-containing drinking water till the end. Mouse...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This study used a transgenic strategy, specifically rats overexpressing the A2A receptor, to characterize the neurobiological mechanisms of ethanol consumption as measured by intermittent access to 20% ethanol (IAE) in a two-bottle choice paradigm. In this model, no change in ethanol consumption was observed in transgenic animals compared to wild type controls during the acquisition/maintenance phase. Following alcohol deprivation (AD), only transgenic rats overexpressing the A2A receptor exhibited escalation of ethanol consumption and drank more (by ca. 90%), but not significantly, ethanol than did the wild type rats. Dur...
Source: Neuroscience - Category: Neuroscience Source Type: research
Authors: Waluga M, Kukla M, Kotulski R, Zorniak M, Boryczka G, Kajor M, Ciupinska-Kajor M, Lekstan A, Olczyk P, Waluga E Abstract Omentin and vaspin are adipokines potentially considered in the development of liver pathology. Irisin is new myokin potentially participating in energy processes in the organisms. The aim of this study was to evaluate the plasma concentration of these cytokines and the relationships of them with selected parameters of laboratory tests and of histopathological changes in selected chronic liver diseases: non-alcoholic fatty liver diseases (NAFLD), primary biliary cholangitis (PBC) and alc...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Publication date: Available online 21 August 2019Source: Food HydrocolloidsAuthor(s): Patricia Cazón, Gonzalo Velazquez, Manuel VázquezAbstractHighly flexible composite films based on bacterial cellulose, glycerol and polyvinyl alcohol (PVOH) with UV barrier properties were developed. The open nanoscale network of bacterial cellulose allowed to combine it with glycerol and polyvinyl alcohol by immersion. This procedure kept intact the bacterial cellulose structure. The interactions among bacterial cellulose, glycerol and PVOH were analyzed using scanning electron microscopy, infrared spectroscopy, thermogravi...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
In this study, consolidated composites are synthesized employing highly porous activated carbon (AC) namely Maxsorb III and two types of binders: (i) polymerized ionic liquid (PIL) and (ii) polyvinyl alcohol (PVA) for the development of compact CO2 based ACS. Adsorption characteristics of composite/CO2 pairs are studied at temperature ranging from 20 to 70 °C and pressure up to 7000 kPa. Experimental adsorption uptake data are fitted with Langmuir, Tóth, Dubinin-Astakhov (D-A) and modified D-A equations. It is observed that composite employing 90 wt% Maxsorb III and 10 wt% PIL shows maximum CO2 adsorptio...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: 1 November 2019Source: Journal of Molecular Liquids, Volume 293Author(s): Ganeshlenin Kandasamy, Atul Sudame, Dipak Maity, Shalini Soni, Kumari Sushmita, Naga Suresh Veerapu, Suryasarathi Bose, C.V. TomyAbstractIn this work, we have developed novel multifunctional magnetic-polymeric nanoparticles (MMPNs) based ferrofluids by encapsulating oleylamine (OM)-coated hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) inside the poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) individually, and along with two drugs such as curcumin (Cur, a chemotherapeutic drug (CHD)), and/or verapamil (Ver,...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Authors: Sue S Abstract The research articles in this special issue edited by Zamboanga and Lui focus on sociocultural factors and processes that underlie ethnic disparities in alcohol use in the United States. Major ethnic minority groups such as African Americans, Asian Americans, and Hispanics are included. Contributors to this special issue present their research findings and draw implications for research, theory, and intervention. The focus is clearly needed. We know enough to say that serious alcohol-use disparities exist; finding effective solutions to these problems is vitally important, especially in our ...
Source: The American Journal of Orthopsychiatry - Category: Psychiatry Tags: Am J Orthopsychiatry Source Type: research
Authors: Lui PP, Zamboanga BL Abstract Hazardous alcohol use is associated with deleterious health effects and social consequences, reduced work productivity, and increased medical and criminal justice expenditures. Research has consistently shown not only ethnic differences in prevalence rates of drinking behaviors and alcohol use disorders but also negative alcohol-related consequences and treatment-seeking patterns. Mainstream alcohol research has tended to focus on determinants and mechanisms that are common across ethnocultural groups; hence, there are tremendous opportunities to address issues that are especi...
Source: The American Journal of Orthopsychiatry - Category: Psychiatry Tags: Am J Orthopsychiatry Source Type: research
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