As Haiti struggles to stamp out cholera, UN urges further international support to combat disease

Noting the challenges that continue to hamper sustained progress in combating cholera in Haiti, the United Nations General Assembly underscored the need to strengthen national health, sanitation and water systems on the island to promote the well-being of the population as well as contributing to Haiti's sustainable development efforts.
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news

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[allAfrica] I witnessed first-hand the devastation of Cyclone Idai in a visit to Mozambique earlier this month. The severe flooding triggered by the cyclone left the water and sanitation systems in ruins. As the spread of cholera became a real risk, it was clear that speed would be critical to save lives and prevent even more suffering among the nearly two million people affected by the cyclone in that country alone. In response, immunization partners mobilized to dispatch some 900,000 doses of the oral cholera vaccin
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 20 April 2019Source: BiologicalsAuthor(s): Mozhdeh Namvarpour, Majid Tebianian, Reza Mansouri, Seyyed Mahmoud Ebrahimi, Shiva KashkooliAbstractAccording to some difficulties against tuberculosis (TB) vaccination, development of new TB vaccines has been noted in recent years. Selection of proper route for vaccination is one of the most important factors for induction of good immune responses. Hence, in this study, the effects of different administration routes, including intranasal (I.N), subcutaneous (S.C) and intramuscular (I.M) on immune responses against Mycobacterium tuberculosis ESAT...
Source: Biologicals - Category: Biology Source Type: research
Publication date: Available online 17 April 2019Source: Microbes and InfectionAuthor(s): Sophia Häfner
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Conclusions Epidemiological studies have repeatedly helped identify definitive triggers for several diseases. As highlighted in this perspective report, previous studies strongly argue for the interplay between intrinsic factors and putative preventable extrinsic triggers/promoters for CTCL. Given the evidence of geographical regional clustering of CTCL patients, CTCL occurrence in unrelated family members and recent evidence implicating S. aureus in the pathogenesis/progression of CTCL, more research is needed to decipher the precise mechanism by which specific environmental exposures may be driving the pathogenesis of t...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
[WHO] An oral cholera vaccine (OCV) campaign targeting some 487 825 people began Tuesday in Zimbabwe in the two districts most affected by cyclone Idai.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[Nation] A Nairobi Hospital staff member has died and seven others are admitted following a cholera outbreak at the premier health facility in the Kenyan capital.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Abstract The aim of this study was to observe the intestinal mucosal/systemic responses triggered by intranasal vaccination using recombinant Trichinella spiralis serine protease (rTsSP) and its capacity to elicit immune protection against larva challenge in a murine model. rTsSP coupled with cholera toxin B subunit (CTB) was used to vaccinate mice via intranasal route. The results revealed that intranasal vaccination with rTsSP plus CTB elicited significantly intestinal local sIgA response and a TsSP-specific systemic antibody response in vaccinated mice. Furthermore, more goblet cells/acidic mucins and IgA-secre...
Source: Experimental Parasitology - Category: Parasitology Authors: Tags: Exp Parasitol Source Type: research
This study gives unprecedented insight into the physiology of VBNC cells and the drastically altered presence of their metabolic and structural proteins. Introduction Changes in the physical and chemical properties of their environment, such as heat, cold and salt stress, oxygen and nutrient deprivation, desiccation and changes in osmolarity, threaten the survival of bacteria, and they have therefore evolved various strategies to evade detrimental effects (Merchant and Helmann, 2012; Alvarez-Ordóñez et al., 2015; Guan et al., 2017). The facultative human pathogen Vibrio cholerae, is common in brackish a...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
The Kenyan capital has experienced a jump in cholera cases, one of the city's top hospitals said on Tuesday, adding that eight of its own staff had been infected with the disease.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
[The Herald] Government, with support from UNICEF, will start rolling out mass cholera vaccination in Chimanimani and Chipinge today targeting about 500 000 people.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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