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Labmade smallpox is possible, study shows

Source: ScienceNOW - Category: Science Authors: Tags: Pharmacology, Toxicology, Science and Policy, Virology In Depth Source Type: news

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LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 214. Question 1 Who first described the phenomenon of malignant hyperthermia? + Reveal the Funtabulous Answer expand(document.getElementById('ddet945038639'));expand(document.getElementById('ddetlink945038639')) Michael Denborough Question 2 Fox&rs...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five apocrine miliaria Charles Maitland fox sign george henry fox john addison fordyce jones fracture malignant hyperthermia michael denborough Newgate pimp Robert Jones smallpox william osler Source Type: blogs
Publication date: February 2018 Source:Current Opinion in Virology, Volume 28 Author(s): Samuel J Hobbs, Jossef F Osborn, Jeffrey C Nolz Epicutaneous delivery of vaccinia virus (VacV) by scarification of the skin generates robust and durable protective immunity, which was ultimately responsible for eradicating smallpox from the human race. Therefore, infection of the skin with VacV is often used in experimental model systems to study the activation of adaptive immunity, as well as the development and functional features of immunological memory. Here, we describe recent advances using this viral infection to identify and c...
Source: Current Opinion in Virology - Category: Virology Source Type: research
Erna Kroon Giliane Trindade The orthopoxviruses (OPV) comprise several emerging viruses with great importance to human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of bovine vaccinia (BV) in South America. Historically, VACV is the most comprehensively studied virus, however, its origin and natural hosts remain unknown. VACV was the primary component of the smallpox vaccine, largely used during the smallpox eradication campaign. After smallpox was declared eradicated, the vaccination that conferred immunity to OPV was discontinued, favoring a new contingent of susceptible individ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Abstract For almost 150 years after Edward Jenner had published the "Inquiry" in 1798, it was generally assumed that the cowpox virus was the vaccine against smallpox. It was not until 1939 when it was shown that vaccinia, the smallpox vaccine virus, was serologically related but different from the cowpox virus. In the absence of a known natural host, vaccinia has been considered to be a laboratory virus that may have originated from mutational or recombinational events involving cowpox virus, variola viruses or some unknown ancestral Orthopoxvirus. A favorite candidate for a vaccinia ancestor has been...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Conclusion The message is clear, as far as governments are concerned: the more often something is repeated, the more likely the public will believe it. Or, in the words of Joseph Goebbels, “If you tell a lie big enough and keep repeating it, people will eventually come to believe it.” [8]   References https://learning.blogs.nytimes.com…history-and-biology-of-vaccines/ http://www.ukcolumn.org/article/magic-madness-governments-nlp-assault-our-minds https://thenib.com/vaccines-work-here-are-the-facts-5de3d0f9ffd0 https://www.popsci.com/16-african-countries-have-overtaken-us-measles-vaccinations https:...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Christina England Logical Top Stories Maki Naro NLP truth about vaccines Source Type: blogs
In 1980, smallpox disease was eradicated from nature and Variola virus, the etiological agent of smallpox, was confined to two laboratories, one located in Russia (Moscow) later moved to VECTOR (Novosibirsk, Sibe...
Source: Virology Journal - Category: Virology Authors: Tags: Methodology Source Type: research
Ricin, anthrax and smallpox were all improperly handled or stored.
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
anier Smallpox (variola) virus is considered a Category A bioterrorism agent due to its ability to spread rapidly and the high morbidity and mortality rates associated with infection. Current recommendations recognize the importance of oral antivirals and call for having at least two smallpox antivirals with different mechanisms of action available in the event of a smallpox outbreak. Multiple antivirals are recommended due in large part to the propensity of viruses to become resistant to antiviral therapy, especially monotherapy. Advances in synthetic biology heighten concerns that a bioterror attack with variola woul...
Source: Viruses - Category: Virology Authors: Tags: Perspective Source Type: research
Authors: Xie J, He Y Abstract Vaccine is the one of the greatest inventions of modern medicine that has contributed most to the relief of human misery and the exciting increase in life expectancy. In 1796, an English country physician, Edward Jenner, discovered that inoculating mankind with cowpox can protect them from smallpox (Riedel S, Edward Jenner and the history of smallpox and vaccination. Proceedings (Baylor University. Medical Center) 18(1):21, 2005). Based on the vaccination worldwide, we finally succeeded in the eradication of smallpox in 1977 (Henderson, Vaccine 29:D7-D9, 2011). Other disabling and leth...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Outbreaks of varicella and monkeypox in Africa are occasionally mistaken for “smallpox”   The following table was generated by an interactive tool in Gideon (www.GideonOnline.com) which allows users to generate custom charts that contrast clinical features, drug spectra or microbial phenotypes.       The post Varicella vs. Monkeypox appeared first on GIDEON - Global Infectious Diseases and Epidemiology Online Network.
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: Diagnosis Epidemiology Examples Microbiology Source Type: blogs
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