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Mauna Kea touts Cellvizio pancreatic cyst diagnosis data

Mauna Kea (ENT:MKEA) today touted the results from a recently published study of its Cellvizio system which supported the use of the device in diagnosing pancreatic cysts. The Cellvizio device is designed for use in a variety of surgical procedures, providing real time visualization at the microscopic level, Mauna Kea said. Results from the study were published in the World Journal of Gastroenterology, the French company said. In the study, researchers evaluated in vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions, Mauna Kea reported. The researchers concluded that in vivo nCLE patterns were reproducible in ex vivo pCLE for all major neoplastic pancreatic cysts. “This new peer reviewed study led by Dr. Krishna provides further validation of the application of Cellvizio needle-based CLE in the diagnosis of pancreatic cysts. There is a significant opportunity for clinicians to use optical biopsy with Cellvizio in the often-challenging task of diagnosing pancreatic cysts, allowing them to make faster diagnoses and better treatment decisions to achieve better outcomes for their patients,” CEO Sacha Loiseau said in a prepared release. In May, Mauna Kea touted data from a study examining the use of its Cellvizio platform in assessing acute lung rejection following transplant. Results from follow-up exams of 24 lung transplant patients were used in the study, with CLE video-imaging obtained prior to tissue sampling, Mauna Kea said. Endomicroscopy...
Source: Mass Device - Category: Medical Devices Authors: Tags: Clinical Trials Imaging Mauna Kea Technologies Source Type: news

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Authors: Huang S, Tang Y, Zhu Z, Yang J, Zhang Z, Wang L, Sun C, Zhang Y, Zhao Q, Chen M, Wu L, Wang D, Ju W, Guo Z, He X Abstract BACKGROUND The inherent challenges of selecting an acceptable donor for the increasing number and acuity of recipients has forced programs to take increased risks, including accepting donors with a cancer history (DWCH). Outcomes of organ transplantation using organs from DWCH must be clarified. We assessed transplant outcomes of recipients of organs from DWCH. MATERIAL AND METHODS Retrospective analysis of the Scientific Registry of Transplant Recipients data from January 1, 2000 to De...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
PMID: 29455798 [PubMed - in process]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Conclusions ML utilizing qCT could discern distinct mechanisms driving FEV1 decline in BOS and non-BOS LTx patients and predict eventual onset of BOS. This approach may become useful to optimize management of LTx patients.
Source: Academic Radiology - Category: Radiology Source Type: research
Renal rejection clinically represents a major cause of graft dysfunction and sadly the loss of the renal transplant. This is despite the considerable progress in immunosuppressive therapy. It is strongly believed that the complex immunologic network underlying the response against major histocompatibility molecules (MHC) is responsible for rejection, an unresolved issue that is, in part, not inhibited by the current prophylactic and therapeutic strategies. Extracorporeal photopheresis (ECP) is an effective cell therapy approach that was successfully used in immunomodulating heart rejection, acute and chronic GvHD, lung rej...
Source: Transfusion and Apheresis Science - Category: Hematology Authors: Tags: Review Source Type: research
In this prospective, single-center, observational study, we sought to investigate the association between repeated short periods of circulatory arrests with moderate hypothermia during pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and different neuropsychological dimensions.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study aimed to describe recipients ’ characteristics, and the frequency and etiology of infections and transplant outcome in liver and lung SOTs, and to investigate exposures associated to infection and death in liver transplant recipients. The study population included recipients of SOTs performed in Italy during a 1-year period i n ten Italian lung transplant units and eight liver transplant units. Data on comorbidities, infections, retransplantation, and death were prospectively collected using a web-based system, with a 6-month follow-up. The cumulative incidence of infection was 31.7% and 47.8% in liver and...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
No abstract available
Source: Transplantation - Category: Transplant Surgery Tags: Commentaries Source Type: research
Short-term outcomes of solid organ transplantation have improved dramatically over the past several decades; however, long-term survival has remained static over the same period, and chronic rejection remains a major cause of graft failure. The importance of donor, or “passenger,” lymphocytes to the induction of tolerance to allografts was recognized in the 1990s, but their precise contribution to graft acceptance or rejection has not been elucidated. Recently, specialized populations of tissue-resident lymphocytes in nonlymphoid organs have been described. These lymphocytes include tissue-resident memory T cel...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
Conclusions Induction with sc28AT promotes early cardiac allograft protection in hu5C8-treated NHPs. These results support further investigation of prolonged selective CD28 inhibition with CD40/CD154 blockade in NHP transplants.
Source: Transplantation - Category: Transplant Surgery Tags: Original Basic Science—General Source Type: research
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