Rapid Growth in Medicaid Spending on Medications to Treat Opioid Use Disorder and Overdose (June 2017)

Report used state Medicaid drug utilization files from 2011 to 2016 to assess spending on buprenorphine, naltrexone, and naloxone prescriptions.
Source: HSR Information Central - Category: International Medicine & Public Health Source Type: news

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CONCLUSION: Although pain perception has multiple complex influences, the greatest variability seen in response to opioids among postoperative patients known to date can be traced to genetic differences in opioid metabolism. Further study is needed to determine the clinical significance of these genetic associations. PMID: 29791710 [PubMed - in process]
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research
AbstractRarely has the introduction of an anesthetic agent or adjunct been as anticipated or needed as that of sugammadex. Residual paralysis after neuromuscular blockade (NMB) occurs frequently and is associated with a range of adverse effects ranging from patient discomfort to respiratory complications and death. Residual neuromuscular block is due to a number of factors that include overdosing of neuromuscular blocking agents (NMBAs), inadequate monitoring of the effect of NMBAs, and the limitations of anticholinesterses to antagonize neuromuscular block (relatively slow onset of effect and inability to antagonize deep ...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
North America is experiencing an overdose epidemic driven in part by the proliferation of illicitly-manufactured fentanyl and related analogues. In response, communities are scaling up novel overdose preventio...
Source: Substance Abuse Treatment, Prevention, and Policy - Category: Addiction Authors: Tags: Commentary Source Type: research
More than 2 million times every year, individuals with serious mental illness are arrested. Moreover, more than half a million people with serious mental illness are incarcerated at any given time. In fact, 44% of jail inmates and 37% of state and federal prisoners have a history of a mental illness.“Those numbers are staggering no matter how you look at them,” said APA President Altha Stewart, M.D., at congressional briefing titled “Innovations and Challenges in Providing Mental Health Services to People in Prison and Those Reentering the Community.” APA was one of the sponsors of the briefing.Driv...
Source: Psychiatr News - Category: Psychiatry Tags: Altha Stewart APA President criminal justice system HR 4005 incarceration Medicaid Rep. Paul Tonko Robert Morgan serious mental illness Source Type: research
The Food and Drug Administration remains concerned about potential abuse of the over-the-counter antidiarrheal loperamide. The agency is working with manufacturers to create packaging that more clearly shows the dose for consumers and to limit the number of doses in one package.Intentional abuse or unintentional overdose of loperamide can lead to serious cardiac complications and possibly death.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
3 out of 5 stars Severe loperamide toxicity associated with the use of cimetidine to potentiate the “high.” Hughes A et al. AM J Emerg Med 2018 May 15 [Epub ahead of print] Reference The potential adverse effects of loperamide (Imodium) are often underestimated since, even though it is an opioid, it is available over-the-counter and has been since 1988. Loperamide is used to treat diarrhea. It acts on the mu-opioid receptors in the gut, decreasing gastric motility. It is rather effective at this. However at therapeutic doses (2-16 mg per day) it does not cause central opioid effects such as euphoria or rel...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical imodium loperamide overdose toxicity Source Type: news
By NIRAN AL-AGBA, MD The University of Southern California (USC) appears to look the other way when male physicians harass or assault women. In reality, sexual violence spares no occupation, including medicine, but the way an organization responds to crime against women indicates a certain level of integrity. The World Health Organization estimates sexual violence affects one-third of all women worldwide. In a nation where women make up 50% or more of each incoming medical school class, only sixteen percent of medical school deans are female, making gender imbalance in leadership positions nearly impossible to overcome. Fo...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: OP-ED Physicians #MeToo Sexual Assault USC Source Type: blogs
When I first became an emergency medical technician, I thought being on an ambulance would be constant excitement: driving with lights and sirens to rescue injured victims of traffic crashes, delivering babies in people’s homes, taking men and women with strokes and heart attacks quickly to the hospital. I soon learned that not every 911 call involved a life-threatening emergency requiring rapid transport. A nursing home resident fell and needed stitches. A child’s fever spiked, causing a seizure. A teenager broke his leg trying to score the winning run. Emergency medical services (EMS) providers do much more t...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Authors: Tags: News Administration and Leadership Source Type: news
THURSDAY, May 24, 2018 -- For non-Hispanic whites, rising fatal drug overdose rates are associated with increases in the mortality rate and years of potential life lost from 1999 to 2015, according to a study published online May 22 in the American...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Journal of Clinical Pharmacy and Therapeutics, EarlyView.
Source: Journal of Clinical Pharmacy and Therapeutics - Category: Drugs & Pharmacology Authors: Source Type: research
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