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Rapid Growth in Medicaid Spending on Medications to Treat Opioid Use Disorder and Overdose (June 2017)

Report used state Medicaid drug utilization files from 2011 to 2016 to assess spending on buprenorphine, naltrexone, and naloxone prescriptions.
Source: HSR Information Central - Category: International Medicine & Public Health Source Type: news

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Condition:   Accidental Overdose of Opiate Intervention:   Behavioral: Take home rapid drug test Sponsor:   Brown University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Funding Opportunity RFA-DA-19-002 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to support the discovery and development of medications to prevent and treat opioid use disorders (OUD) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. UG3 projects that have met their milestones will be administratively conside...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
3 out of 5 stars Fewer adverse effects with a modified two-bag acetylcysteine protocol in paracetamol overdose. McNulty R et al. Clin Toxicol 2017 Dec 8 [Epub ahead of print] Abstract Current recommendations for dosing intravenous N-acetylcysteine (Acetadote) for treating acute acetaminophen (paracetamol) poisoning involves a somewhat complex three-bag protocol, using 3 direct concentrations of the antidote given over a 21-hour period. Unfortunately, this protocol results in a high incidence of (usually mild) adverse events, including cutaneous effects, nausea and vomiting, and anaphylactoid reactions. Severe rea...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical Acetadote acetaminophen antidote N-acetylcysteine paracetamol three-bag protocol toxicity two-bag protocol Source Type: news
[Abstract unavailable] Language: en...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
North America is currently experiencing an overdose epidemic due to a significant increase of fentanyl-adulterated opioids and related analogs. Multiple jurisdictions have declared a public health emergency given the increasing number of overdose deaths. I...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: The opioid epidemic in the United States (US) continues to generate significant increases in morbidity and mortality with no sign of decline. Overdose education and naloxone distribution (OEND) programs are highly effective at preventing opioid...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Conclusions: Medication profiles available through state PMP can identify dosing of prescriptions associated with drug overdose death.Pharmacology 2018;101:140 –147
Source: Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusions: Antioxidant therapy in the form of NAC in severe ALP poisoning did not confer any survival benefit.
Source: Indian Journal of Critical Care Medicine - Category: Intensive Care Authors: Source Type: research
©iStock/windslegend With the current concerns related to opioid addiction and overdose, researchers from the National Institute on Drug Abuse (NIDA) are exploring ways to reduce the use of opioids for pain relief, while still effectively managing pain. In a randomized clinical trial, 422 patients. ..
Source: NIDA News - Category: Addiction Source Type: news
The opioid epidemic in the United States is a critical public health issue. There were 33  091 deaths from opioid overdoses in 2015, which represents a nearly 400% increase since 1999. The role of prescription painkillers in this epidemic cannot be ignored. More than half of these deaths in 2015 involved prescription opioids, and the total amount of oxycodone hydrochloride and hydrocod one bitartrate sold to retail pharmacies has increased by nearly 300% from 2000 to 2016. In this issue ofJAMA Surgery, Chen and colleagues present a timely assessment of the association between inpatient opioid use and opioid prescriptions...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
More News: International Medicine & Public Health | Medicaid | Overdose | Suboxone