LEAF Interviews Gary Hudson of Oisin Biotechnologies

Oisin Biotechnologies is developing a gene therapy approach to the clearance of senescent cells, and here I'll link to an interview with the CEO Gary Hudson conducted by the volunteers of the Life Extension Advocacy Foundation (LEAF). Oisin Biotechnologies is very much a company of our community: seed funded by the Methuselah Foundation and SENS Research Foundation, later angel investors drawn from the audience here, and headed by by one of the earliest supporters of the Methuselah Foundation and the SENS rejuvenation research programs. As regular readers will know, the accumulation of senescent cells is one of the root causes of aging, and targeted destruction of these cells has long been a part of the SENS goal of bringing aging under medical control. Senescent cells make up only a few percent of all cells in aged tissue, but that few percent secretes a potent mix of signals that cause great harm, degrading the proper function of other cells, structures, and organs, and producing chronic inflammation. In the past few years, progress towards the goal of senolytic therapies that can destroy senescent cells has accelerated, with demonstrations of extended life and reversal of many measures of aging in mice. A number of companies are now working on a range of therapies, aiming to bring the first practical, working rejuvenation therapy to the clinic. The Oisin approach is quite different from the therapies under development by the rest of the field, however. Companies suc...
Source: Fight Aging! - Category: Research Authors: Tags: Healthy Life Extension Community Source Type: blogs