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Asbestos Type Has No Effect on Mesothelioma Latency Period

New research from scientists in Germany sheds more light on the unusually long latency period associated with mesothelioma and other asbestos-related diseases. The study, published earlier this year in the European Respiratory Journal, is the first to track the presence of asbestos fibers in lung tissue over time. Mesothelioma has one of the longest latency periods of any cancer. It typically takes anywhere from 20 to 50 years after a person’s initial exposure to asbestos before symptoms arise. Using the German Mesothelioma Register, researchers at Ruhr-University Bochum discovered the volume of asbestos fibers in tissue does not decrease over time, regardless of the type of asbestos involved. Specifically, the concentration of chrysotile — the most common of the six types of asbestos — remained stable over time, despite some previous studies suggesting it may be easier for the body to rid itself of that particular type of the naturally occurring mineral. “Our results show that asbestos continues to be demonstrable in human lungs, that also chrysotile can be identified after many years, and that there is no significant reduction of asbestos fibre concentrations in lung tissues over time after exposure cessation,” lead researcher Inke Sabine Feder wrote in the study. “The unique benefit of the data presented here is to have a measured starting point of the asbestos fibre burden of the human lung tissue to compare later findings with.&rd...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: amosite amphibole asbestos exposure asbestos fiber burden asbestos fibers in lungs biopersistence of asbestos bronchoalveolar lavage Chrysotile asbestos Chrysotile asbestos fibers European Respiratory Journal German Mesothelioma Regist Source Type: news

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Treatment options for malignant mesothelioma may soon include customized gene therapy, according to thoracic surgeon and scientist Dr. Prasad Adusumilli at Memorial Sloan Kettering Cancer Center in New York. Gene therapy involves a laboratory reprogramming of a patient’s own T cells, which are a type of white blood cell, to recognize and destroy the cancer. The U.S. Food and Drug Administration (FDA) recently approved the first gene therapy specifically for pediatric leukemia, signaling the start of a new approach to cancer treatment in this country. The newly approved treatment is also known as chimeric antigen rece...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: CAR T cell therapy checkpoint blockade chimeric antigen receptor T cell therapy Dr. Andy Haas Dr. Prasad Adusumilli Dr. Scott Gottlieb FDA Commissioner gene therapy cancer gene therapy for mesothelioma immunotherapy clinical trial mali Source Type: news
An estimated 38,400 people around the world will die this year from mesothelioma cancer, according to a report recently published in Occupational &Environmental Medicine. The estimation by the international peer-reviewed journal included 230 countries. Data used for the study came from the World Health Organization’s (WHO) Mortality Database and extrapolated information based on gender- and age-specific death rates. “The global burden of mesothelioma is real,” Dr. Ken Takahashi, director of Asbestos Diseases Research Institute, University of Sydney Gate 3, Australia, told Asbestos.com. “It is vi...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: Asbestos Diseases Research Institute asbestos-related lung cancer Australia mesothelioma Bangladesh Dr. Christina Fitzmaurice Dr. Ken Takahashi Global Burden of Disease Mesothelioma death rate mesothelioma latency period mesothelioma uni Source Type: news
This study is the first report about secondary HOA caused by non-pleural or pulmonary tumors. Various primary tumors were identified, including several rare tumors such as sarcomas. HOA is a rare disorder with typically radiologically findings, which is not only associated with lung cancer or pleural mesothelioma and can even occur in tumor patients without lung metastasis.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
The U.S. Department of the Interior has ordered a halt to a study on the public health risks of mountaintop removal mining in Appalachia — an area ripe with natural asbestos deposits. A letter from the Interior Department on Monday directed the National Academies of Sciences, Engineering and Medicine to “cease all work” on the study, citing responsible spending of taxpayer dollars as the reason for the decision. The $1 million National Academies study began in 2016 and was expected to take two years to complete. It aimed to evaluate health risks of a common mining technique for people living near surfac...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: Appalachian Mountains arsenic asbestos exposure Appalachia asbestos exposure coal mining asbestosis coal mining Bill Price Central Appalachia coal mining Appalachia Donald Trump Environmental Health Perspectives Glenda Owens House Co Source Type: news
Health surveillance of formerly asbestos exposed individuals focus on early detection of asbestos related diseases, such as lung fibrosis (asbestosis), pleural plaques, mesothelioma and lung cancer in particul...
Source: Journal of Occupational Medicine and Toxicology - Category: Occupational Health Authors: Tags: Case report Source Type: research
Cancer patients who opt for alternative therapy instead of conventional medicine significantly decrease their chances of survival, according to researchers at Yale School of Medicine. Although the popularity of alternative medicine continues to grow, a recent study published in the Journal of the National Cancer Institute found survival rates significantly reduced for those who use it as first-line therapy. Conventional cancer treatments — chemotherapy, surgery and radiation — still produce a much better chance of survival. Mesothelioma was not included in the study, but the findings are relevant to this rare ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: acupuncture cancer Alternative medicine alternative mesothelioma treatment alternative therapy survival alternative vs conventional medicine breast cancer colon cancer Conventional cancer treatments Dr. David Gorski Dr. Skyler Johnson Source Type: news
A new report from the National Cancer Institute (NCI) shows between 20 and 30 percent of malignant mesothelioma patients do not receive any cancer treatment. The study, “Patterns of care and survival among patients with malignant mesothelioma in the United States,” published August 10 in the journal Lung Cancer, aimed to describe the patterns of care and subsequent survival among mesothelioma patients in the U.S. while adjusting for patient demographics and pre-existing health conditions. Using the NCI’s Surveillance, Epidemiology, and End Results (SEER) data, researchers discovered significant differenc...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: amount of mesothelioma patients eligible for surgery checkpoint inhibitors clinical trial enrollment cytoreduction surgery heated chemotherapy pleural mesothelioma heated intraperitoneal chemotherapy immunotherapy mesothelioma keytruda Lin Source Type: news
The annual cost of asbestos-related occupational disease in Canada is estimated at $2.35 billion, according to new findings by a panel of epidemiologists, public health experts and medical professionals. Their estimate is based on direct, indirect and quality-of-life costs related to the 2,331 patients in Canada diagnosed with mesothelioma or asbestos-related lung cancer in 2011. Occupational and Environmental Medicine, a monthly peer-reviewed medical journal, released the updated report in July. It followed a similar study conducted by the same group of experts in 2016. “When you look at the big picture [and] consid...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: asbestos ban in canada asbestos mines canada asbestosis canada canada mesothelioma Dr. Emile Tompa economic burden asbestos canada financial burden mesothelioma canada health care costs mesothelioma canada House of Commons Occupational a Source Type: news
Learning Module - Matthew D. Hellmann, MD, and Heather Wakelee, MD, examine and discuss key lung cancer and mesothelioma presentations from the 2017 clinical oncology meeting in Chicago.
Source: Clinical Care Options Lung Cancer - Category: Cancer & Oncology Source Type: research
Source: Lung Cancer - Category: Cancer & Oncology Authors: Tags: Research paper Source Type: research
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