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Celebrity doctor warns we should wear toxic sunscreen while talking on our cellphone or using our computer

(Natural News) The fear of getting skin cancer drives many people to wear sunscreen every time they leave the house, even if their plans don’t include spending time outdoors. The sunscreen industry has embraced this line of thinking, which is one big reason that Vitamin D deficiencies are soaring in this country. Melanoma is certainly...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Louise Burgess, 45, from Canberra, was diagnosed with stage one melanoma in May this year after she noticed a mole changed shape last November and used the SkinVision app to track its progress.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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Source: International Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research
Authors: Melo DH, Mamede RCM, Neder L, Silva WA, Barros-Filho MC, Kowalski LP, Pinto CAL, Zago MA, Figueiredo DLA, Jungbluth AA Abstract Despite considerable advances in the understanding of thyroid gland biology, correctly diagnosing thyroid nodules and treating high-grade thyroid carcinoma remains challenging. Cancer/testis (CT) antigens have emerged as potential diagnostic tools as well as targets of potential cancer vaccinations. In the present study, a total of 117 patients who underwent surgical therapy for thyroid disease were available for analysis. The expression levels of melanoma-associated antigen (MAGE...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Tumors depend on their microenvironment for sustained growth, invasion, and metastasis. In this environment, endothelial cells (ECs) are an important stromal cell type interacting with malignant cells to facilitate tumor angiogenesis and cancer cell extravasation. Of note, lysosomal acid lipase (LAL) deficiency facilitates melanoma growth and metastasis. ECs from LAL-deficient (lal−/−) mice possess enhanced proliferation, migration, and permeability of inflammatory cells by activating the mammalian target of rapamycin (mTOR) pathway. Here we report that lal−/− ECs facilitated in vivo tumor angiogene...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Metabolism Source Type: research
Signal-transducing adaptor family member-2 (STAP-2) is an adaptor protein that regulates various intracellular signaling pathways and promotes tumorigenesis in melanoma and breast cancer cells. However, the contribution of STAP-2 to the behavior of other types of cancer cells is unclear. Here, we show that STAP-2 promotes tumorigenesis of prostate cancer cells through up-regulation of EGF receptor (EGFR) signaling. Tumor growth of a prostate cancer cell line, DU145, was strongly decreased by STAP-2 knockdown. EGF-induced gene expression and phosphorylation of AKT, ERK, and STAT3 were significantly decreased in STAP-2&ndash...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Molecular Bases of Disease Source Type: research
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
In conclusion, it should be kept in mind that digital clubbing might be associated with metastatic melanoma to the lung, notwithstanding rarely, and successful treatment of the underlying disease is associated with rapid resolution of the clubbing, as occurs in most patients with paraneoplastic syndromes. PMID: 29164975 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
In this study, we tested the cytotoxicity of several kinase inhibitors, including the glycogen synthase kinase (GSK)‐3 inhibitor CHIR99021, and rapamycin, in combination with a dietary xanthone, α‐mangostin, by screening from a kinase inhibitor library for melanogenesis in SK‐MEL‐2 MM cells, and verified these by clone formation efficiency, terminal dUTP nick end labelling, and expression of apoptosis‐related proteins. We also explored the molecular mechanisms for the apoptosis‐inducing effects reported. We found a marked synergistic effect of CHIR99021 or rapamycin in combination with α‐mangostin...
Source: Clinical And Experimental Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
Disrupting glucose-6-phosphate isomerase fully suppresses the "Warburg effect" and activates OXPHOS with minimal impact on tumor growth except in hypoxia. Oncotarget. 2017 Oct 20;8(50):87623-87637 Authors: de Padua MC, Delodi G, Vučetić M, Durivault J, Vial V, Bayer P, Noleto GR, Mazure NM, Ždralević M, Pouysségur J Abstract As Otto Warburg first observed, cancer cells largely favor fermentative glycolysis for growth even under aerobic conditions. This energy paradox also extends to rapidly growing normal cells indicating that glycolysis is optimal for fast growth and biomass produ...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
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