Immediate Effect of Needling at CV-12 (Zhongwan) Acupuncture Point on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Placebo Controlled Trial

Conclusion The result of this study suggests that 30 minutes of needling at CV-12 might be useful in reducing blood glucose level in patients with T2DM.
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research

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ConclusionIn patients with type 2 diabetes, structural neurogenic characteristics were associated with DR. If confirmed by larger prospective studies, these results may indicate that a complex neurovascular interaction is an early event in the pathogenesis of DR.
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Conditions:   Obesity;   Diabetes Mellitus, Type 2 Interventions:   Drug: JNJ-64565111 Dose Level 1;   Drug: JNJ-64565111 Dose Level 2;   Drug: JNJ-64565111 Dose Level 3;   Drug: Placebo Sponsor:   Janssen Research & Development, LLC Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractPurposeEpidemiological studies had demonstrated that early age at menarche increased the risk of type 2 diabetes (T2DM), and gestational diabetes mellitus (GDM) shares many risk factors and features with T2DM. Thus, age at menarche may be a potential factor in the development of GDM. The aim of this study was to assess the association between age at menarche and the risk of gestational diabetes mellitus.MethodsThe databases of PubMed, Embase, Web of Science and Cochrane Library were searched up to June 2017.ResultsA total of 50,535 participants from five individual studies were included in the meta-analyses to eval...
Source: Endocrine - Category: Endocrinology Source Type: research
ConclusionSince fat accumulation and distribution seem to play a relevant role in triggering metabolic abnormalities, an early diagnosis and a tailored intervention strategy with drugs aimed at targeting excessive visceral fat deposition appear necessary in patients with KS.
Source: Endocrine - Category: Endocrinology Source Type: research
CMS is changing note requirements, among other changes.  Bob Doherty has a wonderful summary – FOUR things you should know about Medicare’s “historic” changes to physician payments As always, we really will have a difficult time sorting out the unintended consequences of these changes, but they certainly seem like a move in the proper direction.  To me the most important change is a focus on notes – “allowing medical decision making to be the basis for documentation, requiring physicians to only document changed information for established patients and to sign-off on basic...
Source: DB's Medical Rants - Category: Internal Medicine Authors: Tags: Medical Rants Source Type: blogs
DiscussionWe hypothesize that T2D patients with microalbuminuria have a medically determined requirement for MOF and that fulfilling this requirement will result in a decrease in AER and related endothelial biomarkers. If confirmed, this may lead to new insights in the dietary management of patients with T2D.Trial registrationNederlands Trial Register,NTR4669, registered on 7 July 2014.
Source: Trials - Category: Research Source Type: clinical trials
This study was done, due to a continuous increase in the risk of obesity and type 2 diabetes in north Indian population, because of lifestyle and genetic variations. Clinically diagnosed subjects of type 2 diabetes mellitus (as per ADA criteria) were taken as cases and age and sex matched subjects without any associated illness were taken as controls. Obesity was estimated by calculating waist circumference and BMI in the study cases and controls. For genetic variation, DNA was isolated with Quaigen kit method and isolated DNA was amplified with PCR. Amplified DNA was resolved in 1% agarose gel electrophoresis. The Hardy &...
Source: Indian Journal of Clinical Biochemistry - Category: Biochemistry Source Type: research
ConclusionsIpragliflozin was well tolerated, effective, and reduced bodyweight over a period of 52  weeks in patients treated with insulin with/without a DPP-4 inhibitor.Clinicaltrials.gov identifierNCT02175784
Source: Diabetology International - Category: Endocrinology Source Type: research
A 42-year-old woman with diabetes mellitus type 2 treated with the sodium–glucose cotransporter-2 inhibitor canagliflozin underwent elective bariatric gastric bypass. The canagliflozin was held for 24 hours preoperatively. She physiologically decompensated on postoperative day 2. Ultimately, she was diagnosed with euglycemic diabetic ketoacidosis that required intensive care management. This diagnosis was challenging to make as the patient never became hyperglycemic. We use this case to discuss the pharmacology and potential risk of perioperative sodium glucose cotransporter-2 inhibitor administration and to advocate...
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research
The global incidence of hepatocellular carcinoma (HCC) has increased to more than 700,000 cases annually. HCC has emerged as the third leading cause of cancer-related mortality worldwide[1]. Type 2 diabetes mellitus (T2DM) is also a global health problem. In 2013, the International Diabetes Federation estimated that there were 380 million diabetics worldwide[2]. Seeing that the incidence of both HCC and T2DM are increasing rapidly, a subset of people must be affected with HCC and T2DM. Clinical data has shown an association between the presence of diabetes and higher incidence and poorer prognosis of HCC, which suggest tha...
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
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