Hypoxia ‐enhanced adhesion of red blood cells in microscale flow

ConclusionsThe approach presented here enabled the control of oxygen tension in blood during microscale flow and the quantification of RBC adhesion in a cost‐efficient and patient‐specific manner. We identified a unique patient population in which RBCs showed enhanced adhesion in hypoxia in vitro. Clinical correlates suggest a more severe clinical phenotype in this subgroup.

Source: Microcirculation - July 10, 2017 Category: Research Authors: Myeongseop Kim, Yunus Alapan, Anima Adhikari, Jane A. Little, Umut A. Gurkan Tags: ORIGINAL ARTICLE Source Type: research