Cardiac resynchronization therapy: mechanisms of action and scope for further improvement in cardiac function

ConclusionsImproving LV preloading by shortening AV delay is an important mechanism through which cardiac function is improved with CRT. There is substantial scope for further improvement if methods for delivering more efficient ventricular resynchronization can be developed.Clinical Trial RegistrationOur clinical data were obtained from a subpopulation of the British Randomised Controlled Trial of AV and VV Optimisation (BRAVO), which is a registered clinical trial with unique identifier: NCT01258829,https://clinicaltrials.gov
Source: Europace - Category: Cardiology Source Type: research