Systematic investigation on the validity of partition model dosimetry for < sup > 90 < /sup > Y radioembolization using Monte Carlo simulation.

Conclusions: PM leads to inaccurate dose estimations due to the exclusion of cross-fire irradiation, i.e. between the tumour and normal liver tissue. Caution should be taken for cases with higher TI and T/N, and lower LS, as they contribute to major underestimation of D&lt;sub&gt;NL&lt;/sub&gt;. For D&lt;sub&gt;L&lt;/sub&gt;, different correction factor for dose calculation may be used for improved accuracy.&#13.
PMID: 28686171 [PubMed - as supplied by publisher]

Source: Physics in Medicine and Biology - July 7, 2017 Category: Physics Authors: Hashikin NAA, Yeong CH, Guatelli S, Abdullah BJJ, Ng KH, Malaroda A, Rozenfeld AB, Perkins AC Tags: Phys Med Biol Source Type: research