Blue-black grassquit ( Volatina jacarina ) leucocyte and average weight reference values
AbstractThe bird speciesVolatina jacarina is popularly known as blue-black grassquit. They are widely distributed geographically and are not considered threatened for extinction. They are popularly domesticated because of their pleasant singing they can be found in many households. That means Veterinarians are sometimes confronted with those animals. This requires a certain knowledge about these birds, including in terms of reference values. Due to the lack of hematological data for this species, the present study aimed to calculate reference values for leukocytes and mean weight for this bird. To this end, 13 blue-black grassquit were captured at a private ranch located in Guarapari (ES), Southeastern Brazil. The birds were weighed for the determination of their average weight. Moreover, blood samples were drawn in order to conduct a leukocyte count. The mean weight found forV. jacarina was 11.7 ± 3.2 g. The average values determined for leukocytes were 53.8 ± 14.6% lymphocytes, 45.1 ± 15.2% for heterophils and 1.2 ± 1.5 for monocytes. The data found was compared with those in the literature, thus contributing to a better knowledge of the species.
Conclusions: Results reveals that developed nitrendipine nanoemulsion gel overcomes the limitation of low penetration and accentuate permeation through albino Wistar rat skin. It was concluded that nanoemulsion gel could be utilized as a potential carrier for transdermal delivery of nitrendipine. PMID: 31976777 [PubMed - as supplied by publisher]
Authors: Rezaie Shirmard L, Ghofrani M, Bahari Javan N, Bayrami S, Tavassoli A, Rezaie A, Amini M, Kebriaee-Zadeh A, Rouini MR, Dinarvand R, Rafiee-Tehrani M, Dorkoosh FA Abstract Uncontrolled distribution of nanoparticles (NPs) within the body can significantly decrease the efficiency of drug therapy and is considered among the main restrictions of NPs application. The aim of this study was to develop a depot combination delivery system (CDS) containing fingolimod loaded poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) NPs dispersed into a matrix of oleic acid-grafted-aminated alginate (OA-g-AAlg) to minimize ...
Authors: Yoshida T, Sako K, Kondo H Abstract High consumption of oil formulations has been reported to reduce the blood exposure of drugs like tacrolimus. Consumption of oil formulations has also been shown to inhibit T-cell production of interleukin-2 (IL-2) compared to solid dispersion formulations (SDFs). However, a large amount of oil causes gastrointestinal side effects such as diarrhea and low compliance. Here, we investigated the feasibility of reducing the amount of oil and substitution of chemically synthetized oils for natural oils in these formulations. Reducing the amount of sunflower oil increased bloo...
CONCLUSIONS: In conclusion, the potential for supersaturation in LBDDS, and the risk of precipitation, was found to be highly drug dependent. The apparent degree of supersaturation was considered a major factor impacting the ability to maintain drug supersaturation upon storage. PMID: 31975613 [PubMed - as supplied by publisher]
Authors: Mailhot Vega RB, Hoppe BS PMID: 31976780 [PubMed - as supplied by publisher]
With a second case of a deadly Chinese virus confirmed in the United States, and four cases under investigation in New York, Buffalo-area hospitals are on alert and preparing as best as they can. The novel coronavirus was first identified in Wuhan, China, in December. More than 850 cases have since been reported worldwide, with more than 40 deaths in China. Transportation has been shutdown with travel restricted for millions in that country as international officials work to contain the di sease. In…