Amiloride and SN-6 Suppress Audiogenic Seizure Susceptibility in Genetically Epilepsy-Prone Rats.

CONCLUSIONS: These findings suggest acid-sensing ion channels and the Na(+) /Ca(2+) exchanger may play an important role in the pathophysiology of inherited AGS susceptibility in the GEPR-3s.
PMID: 24948133 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - June 20, 2014 Category: Neuroscience Authors: Quansah H, N'Gouemo P Tags: CNS Neurosci Ther Source Type: research