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Fentanyl patch forgeries fooling Ontario's pharmacists

Fake fentanyl patches have become a lucrative business in Ontario as addicts and dealers find ways to dupe pharmacists into handing over the highly toxic drug.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Windsor Source Type: news

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A new study shows that men who start drinking as teenagers have a higher risk of liver disease. Dosage counts and current guidelines may be too lax.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news
If we want to talk about the opioid epidemic as an actual epidemic, let’s use the same terms we use for communicable disease: agent, vector/environment, host. Virulence. Transmission. Immunity. The media has done a great job of providing descriptive statistics of the epidemic. And recent oversight, both legislative and advisory, have attempted to focus on altering vector (prescriber) behavior in the wake of apparent failed attempts to reduce agent virulence. What seems to be lacking in the overall discussion though, in my opinion, is a focus on the host. That is where eradication of epidemics has generally been more ...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Pain Management Primary Care Source Type: blogs
This study from Germany aimed to find out whether the BAITS is an appropriate instrument for screening individuals with symptoms of a potential indoor tanning addiction. The study is based on data from the National Cancer Aid Monitoring on Sunbed Use (NCAM) consisting of cognitive interviews and a nationwide representative telephone survey. Statistical analysis showed that the BAITS seems to be a valid and reliable tool. Altogether, 19.7% of current and 1.8% of former tanning bed users screened positive for symptoms of a potential indoor tanning addiction. However, this is not a final diagnosis of indoor tanning addiction....
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Plain Language Summary Source Type: research
Arizona officials' plan to deal with the rising crisis of opioid addiction is to limit the amount of pills doctors could prescribe. Legislation coming from Gov. Doug Ducey would seek to bar physicians from prescribing more than five days of the pain killers at a time and cap the amount of pills given to people who suffer from chronic pain, according to Ktar.com. The limits as well as increased regulation of pain clinics would be part of the plan. The legislation, however, has not been finished. Opiods…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Authors: Bryant KG, Chae YC, Martinez RL, Gordon JC, Elokely KM, Kossenkov AV, Grant S, Childers WE, Abou-Gharbia M, Altieri DC Abstract Reprogramming of mitochondrial functions sustains tumor growth and may provide therapeutic opportunities. Here, we targeted the protein folding environment in mitochondria by coupling a purine-based inhibitor of the molecular chaperone Heat Shock Protein-90 (Hsp90), PU-H71 to the mitochondrial-targeting moiety, triphenylphosphonium (TPP). Binding of PU-H71-TPP to ADP-Hsp90, Hsp90 co-chaperone complex or mitochondrial Hsp90 homolog, TRAP1 involved hydrogen bonds, π-π stacking...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Drug deaths draw the most notice, but more addicted people live than die. For them and their families, life can be a relentless cycle of worry, hope and chaos.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Addiction (Psychology) Opioids and Opiates Mental Health and Disorders Families and Family Life Heroin Source Type: news
Authors: Fu R, Mei Q, Zuo W, Li J, Gregor D, Bekker A, Ye J Abstract It is unclear how social drinking can contribute to the development of addiction in susceptible individuals. However, alcohol's aversive properties are a well-known factor contributing to its abuse. The lateral habenula (LHb) is a key brain structure responding to various aversive stimuli, including those related to alcohol. We recently reported that ethanol at 10 mM or less that can be achieved by social drinking activates many LHb neurons and drives aversive conditioning. The current study sought to identify LHb circuits that are activated by a ...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research
Authors: Xu E, Liu J, Wang X, Xiong H Abstract Drug abuse disorders refer to a set of related negative health implications associated with compulsive drug seeking and use. Because almost all addictive drugs act on the brain, many of them cause neurological impairments after long-term abuse. Neuropathological studies have revealed a widespread impairment of the cellular elements. As the key components to limit the damage of neural cells, CNS immune system is also found affected by these drugs, directly or indirectly. It has been shown that drugs of abuse alter neuroimmune gene expression and signaling. Growing studi...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research
Conclusion: Our findings revealed a paradigm that highlights the cooperation of ALK, FGFR2 and EphA5 kinases in governing growth advantage of HCC cells, which might offer a novel conceptual “combined therapeutic target” for diagnosis and subsequent intervention in subgroup of HCC patients. This article is protected by copyright. All rights reserved.
Source: Hepatology - Category: Internal Medicine Authors: Tags: Hepatobiliary Malignancies Source Type: research
To assess the relationship of restrictions on Medicaid benefits for addiction treatment to Medicaid acceptance among addiction treatment programs.
Source: Journal of Substance Abuse Treatment - Category: Addiction Authors: Source Type: research
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