S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research.
CONCLUSIONS: S-adenosylmethionine holds promise as a treatment for multiple neuropsychiatric conditions, but the body of evidence has limitations. The encouraging findings support further study of SAMe in both psychiatric and comorbid medical illnesses. PMID: 28682528 [PubMed - in process]
ConclusionsAdjunctive NAC appears to be a safe treatment that has efficacy for schizophrenia, but not for bipolar disorder or MDD. Further higher quality RCTs are warranted to determine the role of adjunctive NAC in the treatment of major psychiatric disorders.
DEMENTIA affects around 850,000 people in the UK, but early signs of the condition can be hard to detect. A new study has suggested restless sleep can be one of the first symptoms of Alzheimer ’s disease.
Yuchen Nan, Chunyan Wu, Qin Zhao, Yani Sun, Yan-Jin Zhang, En-Min Zhou
KEEPING fit in older age helps stave off Alzheimer ’s disease, according to research. Scientists have discovered that bursts of exercise, such as a bike ride or a brisk walk, boost “white matter” tissue found deep within the brain.
PMID: 29453939 [PubMed - in process]
This article provides an overview of classic as well as new, cutting-edge neuroimaging techniques that can assist with clinical diagnosis of Alzheimer disease and other dementia syndromes.Seminars in Neurology
Abstract The purpose of this study was to compare the efficacy of nucleoside analogues (NAs) in the treatment of HBV-related liver failure. The data of patients with HBV-related liver failure treated with nucleoside analogues were used to conduct a network meta-analysis. A total of 1660 patients from 12 articles about the efficacy of lamivudine, entecavir, telbivudine and tenofovir for HBV-related liver failure treatment were recruited in the study. The highest two- and three-month survival rate was recorded for patients using tenofovir. The end-stage liver disease (MELD) score and mortality in patients undergoing...
Researchers find elderly people with high cognitive function have more of a certain type of brain cell“Superagers” have long puzzled scientists, but now researchers say they are unpicking why some people live beyond 80 – and still appear to be in fine fettle, with cognitive capacities on a par with adults decades younger.Researchers have spent years studying superagers in an attempt to understand what sets the senior citizens apart.Continue reading...
AbstractThe present study examined the role of anxiety sensitivity (AS; fear of the negative consequences of anxiety) in the relation between perceived racial discrimination and pain-related problems among Latinos seeking health services at a Federally Qualified Health Center. Participants included 145 adult Latinos (87.80% female,Mage = 38.07 years,SD = 11.98, and 96.2% reported Spanish as their first language). Results indicated that perceived racial discrimination was indirectly related to the pain intensity and pain disability through AS. These effects were evident above and beyond the variance ...
ConclusionsPenicillamine followed by zinc may be a safe and effective treatment in resource-constrained setting for symptomatic hepatic WD patients in all grades of baseline disease severity. Some patients with decompensated cirrhosis due to WD may be managed with medical treatment, avoiding liver transplantation.
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