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S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research.

CONCLUSIONS: S-adenosylmethionine holds promise as a treatment for multiple neuropsychiatric conditions, but the body of evidence has limitations. The encouraging findings support further study of SAMe in both psychiatric and comorbid medical illnesses. PMID: 28682528 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

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Anxiety can mean many different things to many different people. When handled in the correct way, a little bit of anxiety is usually helpful. It warns us to be careful if we sense danger. It can remind us of consequences we once had to live with. By maintaining some anxiety around these issues, we are able to avoid unwanted outcomes. Obsessive compulsive disorder stems from a healthy type of anxiety and morphs into something all-consuming. OCD is a psychiatric disorder that involves repeated and unwanted intrusive thoughts, feelings, ideas, and behaviors that must be done over and over again. While checking to make sure t...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic OCD Psychology Psychotherapy Anxious Thoughts Avoidance Compulsions Obsessions ritualistic behavior Rituals Worry Source Type: blogs
Now we know why some men undo more shirt buttons than they should. • Try one of PsyBlog's ebooks, all written by Dr Jeremy Dean: Activate: How To Find Joy Again By Changing What You Do (NEW) The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Psychology Source Type: blogs
There has been a long debate, since mammograms were put into use in the early 1980s, if they over or under diagnose breast cancer. Now someone has finally decided totake another look at all this data. There are two main parts to this issue: Are small tumors that would never grow into something'bad'being over diagnosed and over treated? Are too many other tumors missed in mammograms? This group of researchers examined data from 2001 to 2013 and determined that:" The results showed that most overdiagnosis occurred in older patients with biologically favorable, slow-growing tumors. "These tumors are ones that will n...
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: breast cancer cancer diagnosis cancer research mammogram Source Type: blogs
AGOMELATINE FOR THE TREATMENT OF GENERALIZED ANXIETY DISORDER. Expert Opin Pharmacother. 2017 Jul 21;: Authors: Buoli M, Grassi S, Serati M, Altamura AC Abstract INTRODUCTION: Agomelatine is a melatonergic antidepressant, approved for the treatment of Major Depressive Disorder (MDD) in Europe and Australia, but not in the United States. This compound seems to be promising in the short-term and maintenance treatment of Generalized Anxiety Disorder (GAD). Areas covered: This paper presents an evaluation of the available data about the clinical efficacy and tolerability of agomelatine in the treatment of ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Rizzetto M Abstract INTRODUCTION: Treatment of chronic hepatitis D still relies on Interferon. To improve efficacy, new therapeutic strategies are in development which aim to deprive the Hepatitis D Virus (HDV) of functions of the Hepatitis B Virus and of the host required for its life-cycle. Areas covered: The therapeutic options are; 1) The inhibition of the farnesylation of the large HD-protein permissive of virion assembly with Lonafarnib, 2) The blocking of HBsAg entry into cells with Myrcludex B via the inhibition of the Sodium Taurocholate Cotransporting Receptor, to prevent the spreading of HDV to ...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
In this study, we asked how POD is influenced by different experimental practices and how likely it is that underpowered experiments lead to scientific disputes between two groups conducting identical experiments. To address these questions, we generated a parametric model based on the Gompertz equation using lifespan data of 5,026 C. elegans. We then used this model to simulate lifespan experiments with different conditions to determine how experimental parameters affect the ability to detect lifespan increases of certain sizes. We considered two important experimental features that contribute to the workload of lifespan ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We report a rare case of a 17-year-old girl with seronegative neurobrucellosis and depression and diplopia. Results of agglutination tests for Brucella both in serum and CSF were negative. Diagnosis was made only by positive culture of Brucella mellitensis with inoculation of the patient’s cerebrospinal fluid in a BACTEC 9050 System. The patient was successfully treated using ceftriaxone, doxycycline and rifampicin therapy for six months.  
Source: Annals of Saudi Medicine - Category: General Medicine Tags: ISSUE 5 Source Type: research
CONCLUSIONS: Diapulse can be considered a disease modifying therapeutic procedure and could be a reliable option for treatment of OA patients. PMID: 28730231 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
CONCLUSIONS: The present findings may be added to accumulated evidence on macroscopic and microscopic pathology of the cerebellum in schizophrenia. Morphological alterations of Purkinje cells seem to be a central feature of neuropathology of schizophrenia, reflecting to impairment of neuronal connectivity and functionality, and related to motor and cognitive symptoms. PMID: 28730225 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Hey all. I wanted to ask about you guys' experience as MS3/4 going through clinical rotations and maybe get some advice. It's my third month in and I'm having mixed feelings about working with residents and attendings. I had a great time with one of my surgery teams -- woke up super motivated every day and looked forward to going in even on weekends. I really felt like I was part of the team and was making contributions to patient care. But on both my other services, I've had a hard time... Feeling awkward &depressed in MS3
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Source Type: forums
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