As it pushes forward with its acne drug, Novan's cash dwindles to $30 million
With cash dwindling, Morrisville-based Novan (Nasdaq: NOVN) is continuing to push forward with its nitric-oxide based acne product SB204 on the heels of a leadership change and workforce reduction. Earlier this year, the company announced mixed Phase 3 clinical trial results for SB204, which sent its stock plummeting 75 percent. Shortly thereafter, Novan said it had assembled a team to analyze the data from those trials and that it continues to remain optimistic on the product and a pre-subm ission…
Authors: Mansouri P, Azizian Z, Najafi Z, Hejazi S, Younespour S Abstract BACKGROUND: Oral Isotretinoin (13-cis-retinoic acid)is a gold standardtreatment for severe forms of acne with cheilitis as a most frequent complication.we designed this novel study to investigate the therapeutic effect of Trichloroacetic Acid(TCA) 33% as compared with placebo to treat cheilitis. METHODS: In this pilot study, 90 acne vulgaris patients between 18 to 50 years, who refered dermatologic clinic with cheilitis, were assigned to either case (TCA) or control (Vaseline) group using permuted-block randomization from 2013 to 2015,wit...
CONCLUSIONS: Fourteen prospective studies representing 671 participants were included in this review. Modalities investigated included face washing frequency, true soap/syndet cleansing bars, antiseptic cleansers, alpha and beta-hydroxy (i.e. salicylic) acid cleansers, and several proprietary formulations. Given the low number of well-performed clinical studies of cleansers and washing, it is difficult to formulate reliable recommendations. We hope that our findings highlight the necessity of further investigation in this area. PMID: 29460655 [PubMed - as supplied by publisher]
CONCLUSION: Once-daily dapsone gel, 7.5% was effective, safe, and well tolerated in patients with all skin phototypes who were treated for moderate acne. J Drugs Dermatol. 2018;17(2):160-167. PMID: 29462223 [PubMed - in process]
How effective are light-based interventions for acne vulgaris?The British Journal of Dermatology
A number of diseases are treated using light therapy. These include acne, actinic keratosis, jaundice, Paget’s disease, and psoriasis. Modern light blankets use arrays of LEDs to produce illumination, but light emitted by LEDs can be quite...
In the first year after a new diagnosis of acne, patients ’ risk for a diagnosis of major depressive disorder spikes by more than 60 percent compared to the general population, a new study shows.Reuters Health Information
A look at chest acne, a condition where acne appears on the chest. Included is detail on when to see a doctor and lifestyle changes that might prevent it.
A look at nose acne, a common condition with a range of causes. Included is detail on the different types of nose acne and ways to prevent them.
Learn how to treat pimples or zits on your scalp. We will cover how to identify scalp acne, home remedies, medicated shampoos, and lifestyle changes.
The singer posted an Instagram story about the unhelpful things people say to acne sufferers like her.