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NIH awards $8.6 million for bold bid to transform lung transplantation

(University of Virginia Health System) Researchers at the University of Virginia School of Medicine have received more than $8.6 million in federal grants to support efforts that could dramatically increase the number of lungs available for transplant - and then save the lives of the people who receive them.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

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Summary Depressive symptoms are common among lung transplant candidates and have been associated with poorer clinical outcomes in some studies. Previous studies have been plagued by methodologic problems, including small sample sizes, few clinical events, and uncontrolled confounders, particularly perioperative complications. In addition, few studies have examined social support as a potential protective factor. We therefore examined the association between pretransplant depressive symptoms, social support, and mortality in a large sample of lung transplant recipients. As a secondary aim, we also examined the associations ...
Source: Transplant International - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
Authors: Copur MS, Wurdeman JM, Nelson D, Ramaekers R, Gauchan D, Crockett D Abstract Solid tumors involving glandular organs express mucin glycoprotein which is eventually shed into the circulation. As aresult these proteins can easily be measured in the serum and be used as potential tumor markers. The most commonly used tumor markers for breast cancer are CA 27-29 and CA 15-3, which both measure the glycoprotein product of the mucin-1 (MUC1) gene. CA 27-29 has been approved by the US Food and Drug Administration for monitoring disease activity in breast cancer patients. Most oncology clinical practice guidelines...
Source: Oncology Research - Category: Cancer & Oncology Tags: Oncol Res Source Type: research
We report here the case of a woman who underwent bilateral lung transplantation for severe emphysema. On day 25 after transplantation, endobronchial green‐black lesions were detected during routine endoscopy. Endobronchial swabs, biopsies, and bronchoalveolar lavage samples were positive for Microascus cirrosus. This fungal infection developed despite voriconazole given for previous persistent invasive aspergillosis. Treatment consisted of a combination of antifungal medication (voriconazole, terbinafine, amphotericin B, and caspofungin) and endoscopic resection of necrosed bronchial mucosa. A favorable clinical outcome ...
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Tags: CASE REPORT Source Type: research
Mehra M. Challenges, diligence, and a breakthrough in donation after circulatory death in heart transplantation. J Heart Lung Transplant 2017;36(12):1319-1321.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Conclusions Hypercapnia ameliorated acute cellular rejection in a rat lung transplantation model.
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Tuesday, December 12, 2017 - 08:26Slide presentation
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Max Olivares has a rare heart and lung condition, which requires a complex transplant operation.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
Each individual BMI unit is an independent predictor of short- and long-term mortality after lung transplantation, and the patterns of this effect are not associated with predefined BMI categories.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
This study represents the first linkage analysis between Pedimacs and Pediatric Heart Transplant Study databases to determine the effects of VAD course on post-transplant outcomes.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
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Source: Clinical Transplantation - Category: Transplant Surgery Authors: Tags: Brief Communication Source Type: research
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