Antinociceptive Activity of Methanol Extract of < b > < i > Tabebuia hypoleuca < /i > < /b > (C. Wright ex Sauvalle) Urb. Stems

Objective: The aim of this study was to evaluate the antinociceptive activity of the methanol extract ofTabebuia hypoleuca stems (THME).Materials and Methods: The animals were divided into 5 groups of 8 mice for each test (negative controls, positive controls, and 3 groups treated with THME at doses of 150, 300, and 500 mg/kg, p.o.). The antinociceptive effect of THME was evaluated using the writhing, formalin, tail flick, and hot plate models in mice.Results: In the writhing test, THME (150, 300, and 500 mg/kg) produced significantly (p
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research