Changes of Bladder M1,3 Muscarinic Receptor Expression in Rats Fed with Short ‐Term/Long‐Term High‐Fat Diets

ConclusionsHigh‐fat diet induces obesity and polyphagia in rats. Short‐term and long‐term HFD feeding decrease rat bladder M1 and M3 receptor expressions as well as contractile responses to the agonistic stimulation. In addition, bladder muscle dysfunction develops after long‐term HFD feeding.

Source: LUTS: Lower Urinary Tract Symptoms - May 1, 2017 Category: Urology & Nephrology Authors: Chian ‐Shiung LIN, Tony T.‐L. WU, Chin‐Hong CHANG, Juei‐Tang CHENG, Yat‐Ching TONG Tags: ORIGINAL ARTICLE Source Type: research