Older males 'reduce IVF conception rates'

Study suggests male age is a significant factor in successful births Related items fromOnMedica Men with infertility at risk of general health issues Fertility treatment explains most birth complications of older mums Women doing heavy or shift work have lower fertility First UK approval for gene editing on human embryos Obese couples take longer to achieve pregnancy
Source: OnMedica Latest News - Category: UK Health Source Type: news

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ConclusionCompared to non-PCOS patients, PCOS patients had greater postoperative ΔBMI and %EWL at 1 year. The majority of patients becoming pregnant after VSG were previously nulliparous. This study shows that VSG is effective for weight loss in PCOS patients with obesity and may positively augment effect fertility rates.
Source: Obesity Surgery - Category: Surgery Source Type: research
Authors: Artini PG, Obino MER, Sergiampietri C, Pinelli S, Papini F, Casarosa E, Cela V Abstract INTRODUCTION: Polycystic ovary syndrome (PCOS) is a common cause of female infertility affecting multiple aspects of a women's health. Areas covered: The aim of this review is to summarize the existing evidence on the treatment of PCOS patients and to examine the actual available therapies to overcome the problem of infertility and improve the outcome of pregnancy. We analyse different treatment strategies such as lifestyle modification, bariatric surgery, insulin sensitizing agents, inositol, clomiphene citrate (CC), a...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Abstract Context: Women with PCOS are at increased risk for pregnancy complications possibly related to pre-existing obesity and potentially to excessive gestational weight gain (GWG). Objectives: To assess the contributions of pre-existing diagnosis and preconception weight on GWG and perinatal outcomes. Research Design and Methods: Prospective cohort study of singleton pregnancies in PCOS(N =164) and ovulatory controls(N = 176) conceiving from infertility treatment. Main Outcome measures: GWG, birthweight, pregnancy complications. Results: From pre-conception baseline, normal-weight PCOS women gai...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Uterine myomas are common benign monoclonal tumors with extremely low potential for malignancy. They are estimated to be present in up to 70% of women of reproductive age [1], with a higher incidence in obese women and those of African American descent, and when symptomatic, a frequent indication for gynecologic surgery. Although the presence of myomas may be associated with a plethora of symptoms including pelvic pain, abnormal uterine bleeding, infertility/subfertility, and adverse pregnancy outcomes [2], the vast majority of women with uterine fibroids are asymptomatic.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Perspective Source Type: research
Uterine myomas are common benign monoclonal tumors with extremely low potential for malignancy. They are estimated to be present in up to 70% of women of reproductive age [1], with a higher incidence in obese women and those of African American descent and, when symptomatic, a frequent indication for gynecologic surgery. Although the presence of myomas may be associated with a plethora of symptoms including pelvic pain, abnormal uterine bleeding, infertility/subfertility, and adverse pregnancy outcomes [2], the vast majority of women with uterine myomas are asymptomatic.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Perspectives Source Type: research
CONCLUSION: First line management of infertility once a diagnosis of PCOS is made should include weight loss and exercise with goals to below class 2 obesity (BMI
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
AbstractSTUDY QUESTIONIs preconception dietary intake associated with reduced fecundity as measured by a longer time to pregnancy (TTP)?SUMMARY ANSWERLower intake of fruit and higher intake of fast food in the preconception period were both associated with a longer TTP.WHAT IS KNOWN ALREADYSeveral lifestyle factors, such as smoking and obesity, have consistently been associated with a longer TTP or infertility, but the role of preconception diet in women remains poorly studied. Healthier foods or dietary patterns have been associated with improved fertility, however, these studies focused on women already diagnosed with or...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
CONCLUSIONS: Preconception intervention with low-dose liraglutide added to metformin is superior to metformin alone in increasing PRs per ET and cumulative PRs in infertile obese women with PCOS, despite comparable weight reduction in both groups. A potential direct crosstalk between GLP-1 and reproductive system needs further exploration. PMID: 29703793 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Tags: Eur J Endocrinol Source Type: research
We examined relationships between maternal age (modeled flexibly to allow curvilinear shapes) and pregnancy outcomes using logistic regression. We plotted absolute predicted risks to display curves from age 20 to 50 estimated for two risk profiles: (1) population average values of all risk factors; (2) a low-risk profile without preexisting diabetes/hypertension, smoking, prior spontaneous/therapeutic abortion, diagnosed infertility, inadequate prenatal care, low income, rural residence, or obesity. Results: Risks of hypertensive disorders increased gradually until age 35, then accelerated. Risk of multiple gestations, ...
Source: Epidemiology - Category: Epidemiology Tags: Reproductive and Perinatal Source Type: research
(Natural News) According to the results of a study, women who take metformin, a common diabetes medication, could be putting their children at increased risk of being obese or overweight. More pregnant women with gestational diabetes or polycystic ovary syndrome (PCOS) are taking metformin to treat their conditions. PCOS usually causes infertility, and the condition can put...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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