Hate outpatient

MS3 here. I'm interested in a lot of things tbh. I liked neuroscience in preclinical years, but soon realized there was little neuroscience in neurology. I liked radiology, reading studies was amazing. Anesthesia and critical care was brilliant. I liked inpatient medicine and surprisingly, I loved rounds. Now I'm on outpatient medicine and if I have to see another metabolic syndrome patient I will most likely OD on insulin. I posted earlier on how I wanted to pursue a rheumatology... Hate outpatient
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Source Type: forums

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Abstract The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low intracellular heme oxygenase (HO-1), making them particularly vulnerable to the disease. Additionally, COVID-19's heme reduction may contribute to even lower HO-1. Low-grade inflammation associated with these risk factors contributes to triggering a cytokine storm that spreads to multi-organ failure and near death. The high mortality of those treated with ventilator ...
Source: Cell Stress and Chaperones - Category: Cytology Authors: Tags: Cell Stress Chaperones Source Type: research
Publication date: Available online 21 April 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Shuhan J. Reyes, Taylor Pak, Tiffany Sun Moon
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
In this study, we intravenously administrated the young mitochondria into aged mice to evaluate whether energy production increase in aged tissues or age-related behaviors improved after the mitochondrial transplantation. The results showed that heterozygous mitochondrial DNA of both aged and young mouse coexisted in tissues of aged mice after mitochondrial administration, and meanwhile, ATP content in tissues increased while reactive oxygen species (ROS) level reduced. Besides, the mitotherapy significantly improved cognitive and motor performance of aged mice. Our study, at the first report in aged animals, not only prov...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The objective of this study was to examine the effect of metabolic syndrome on 30-day postoperative complications following corrective surgery for the adult spinal deformity (ASD). Summary of Background Data: Metabolic syndrome has been shown to increase the risk of cardiovascular morbidity and mortality. Few studies have examined the effect of metabolic syndrome on patients with ASD undergoing surgery. Materials and Methods: We performed a retrospective cohort study of patients who underwent spinal fusion for ASD. Patients were divided into 2 groups based on the presence or absence of metabolic syndrome, which was d...
Source: Journal of Spinal Disorders and Techniques - Category: Surgery Tags: Primary Research Source Type: research
Conclusions: Well-controlled metabolic syndrome did not affect the changes in perioperative blood pressure during cataract surgery with topical anesthesia.
Source: Asia-Pacific Journal of Ophthalmology - Category: Opthalmology Tags: Original Clinical Study Source Type: research
CONCLUSION: Obese patients require comprehensive preoperative evaluation. Experienced medical teams, appropriate equipment and monitoring, careful anaesthetic management, and an adequate perioperative ventilation strategy may improve postoperative outcomes. Additional perioperative precautions are necessary in patients with severe morbid obesity, metabolic syndrome, untreated or severe obstructive sleep apnoea syndrome, or obesity hypoventilation syndrome; patients receiving home ventilatory support or postoperative opioid therapy; and obese patients undergoing open operations, long procedures or revisional surgery. P...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
ConclusionsHFD has no significant effects on neuronal apoptosis or neuroinflammation in acute stage compared with ND for 8  weeks after moderate TBI in experimental rats.
Source: Neurocritical Care - Category: Neurology Source Type: research
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; &AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regio...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
METABOLIC SYNDROME is a low-grade proinflammatory condition associated with numerous pathophysiological mechanisms that can lead to cardiovascular disease, insulin resistance, increased oxidative stress, endothelial dysfunction, and dyslipidemia.1 –5 Metabolic syndrome is a clustering of at least 3 of 5 medical conditions including waist circumference>40 inches in men and>35 inches in women; blood pressure>130/>85 mmHg; serum triglycerides>150 mg/dL; fasting blood glucose>110 mg/dL; and high-density lipoprotein (HDL) levels
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Case Report Source Type: research
In conclusion, the impaired in situ activity of RyR2 may also account for the poor overall cardiac outcome reported in MetS patients; hence, the SERCA pump and RyR2 are both attractive potential targets for future therapies. Introduction Metabolic syndrome (MetS) is a cluster of biochemical and physiological risk factors for cardiovascular disease and diabetes mellitus type 2 (DM2); it represents a severe public health problem around the world (Alberti et al., 2009). Risk factors for MetS include obesity (particularly central obesity), elevated triglyceride (TG) levels, low high-density lipoprotein cholesterol (HDL...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
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