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The bisphosphonate may be an option for mesothelioma patients who are not benefitting from other treatments.(PRWeb July 01, 2017)Read the full story at http://www.prweb.com/releases/2017/07/prweb14478826.htm
Source: PRWeb: Medical Pharmaceuticals - Category: Pharmaceuticals Source Type: news

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The influential American Chemistry Council in Washington, D.C., would likely drop its opposition to an across-the-board ban on asbestos provided an exemption remains for the chlor-alkali industry. Mike Walls, ACC vice president for regulatory affairs, clarified his position last month during a congressional Environment and Climate Change subcommittee hearing to discuss the latest legislative effort to ban all asbestos. “We certainly are not opposing a ban for all other uses of asbestos. I just want to make that clear,” Walls said. “The ACC’s opposition [on legislation] is focused on the impact on t...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Conclusion: Use of CT scans to triage an appropriate pleural biopsy method is associated with high diagnostic success. We recommend that the proposed diagnostic workup in this study may be used as a diagnostic algorithm for pleural diseases that require a histopathologic analysis. Determination of risk factors predicting malignant disease in patients where fibrinous pleuritis is reported after MT would be useful for clinical practice.
Source: Journal of Bronchology and Interventional Pulmonology - Category: Respiratory Medicine Tags: Original Investigations Source Type: research
ConclusionWe conclude that diaphragm interventions are an essential part of CRS. They are associated with increased perioperative morbidity. This morbidity is not attributable to whether the patient underwent diaphragm stripping or resection. However in mesothelioma and LAMNs, requiring diaphragm resection is likely to be an indicator for tumor aggression.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Abstract A cluster of nine mesothelioma cases was observed among 341 registrants' deaths in the US Transuranium and Uranium Registries. Descriptive analysis showed that mesothelioma cases had the highest average cumulative external radiation dose compared with lung cancer, other cancer, and noncancer deaths. Further analysis indicated that the mesothelioma cluster was very different demographically from lung cancer, other cancer, and noncancer deaths. Therefore, an internally matched case-control approach was applied to evaluate the differences in an average cumulative external radiation dose between mesothelioma ...
Source: Health Physics - Category: Physics Authors: Tags: Health Phys Source Type: research
Modern Pathology, Published online: 23 June 2019; doi:10.1038/s41379-019-0309-6Hemizygous loss of NF2 detected by fluorescence in situ hybridization is useful for the diagnosis of malignant pleural mesothelioma
Source: Modern Pathology - Category: Pathology Authors: Source Type: research
Modern Pathology, Published online: 23 June 2019; doi:10.1038/s41379-019-0310-0MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma
Source: Modern Pathology - Category: Pathology Authors: Source Type: research
ConclusionsComplete CRS and HIPEC can be achieved in strictly selected patient with unresectable PM at diagnosis after repeated PIPAC session with palliative intent.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Linda Reinstein was not surprised by the news last week that Colombia had joined the growing list of more than 60 countries to legislate a ban of asbestos. She saw it coming when she spoke on the topic at the University of Rosario in Bogota, Colombia, almost a year ago. She felt the intense passion there to prevent more innocent lives being lost to asbestos-related diseases such as mesothelioma. “It was another experience where the heartache, grief and anger of asbestos victims all came together and turned into action to facilitate change,” Reinstein, president and CEO of the Asbestos Disease Awareness Organiza...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
IFN-γ upregulates membranous and soluble PD-L1 in mesothelioma cells: potential implications for the clinical response to PD-1/PD-L1 blockade. Cell Mol Immunol. 2019 Jun 19;: Authors: Pistillo MP, Carosio R, Banelli B, Morabito A, Mastracci L, Ferro P, Varesano S, Venè R, Poggi A, Roncella S PMID: 31217525 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Immunology - Category: Molecular Biology Authors: Tags: Cell Mol Immunol Source Type: research
Abstract In regional chemotherapy of the pleural space a differentiation is made between intrapleural hyperthermic perfusion (IHP) and hyperthermic intrathoracic chemotherapy (HITOC). The HITOC in particular is carried out as an additive procedure after surgical cytoreduction of the pleural tumor manifestation. The main indications are for malignant pleural mesothelioma and thymoma with pleural spread (stage IVa), whereas treatment of secondary pleural carcinomatosis is indicated only in selected patients suitable for resection followed by HITOC. Cisplatin is the standard chemotherapeutic agent and a concentr...
Source: Der Chirurg - Category: Surgery Authors: Tags: Chirurg Source Type: research
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