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7 medtech stories we missed this week: June 30, 2017

[Image from unsplash.com]From ConforMIS touting its knee replacement study to Consulting Radiologists’s new breast cancer detection tool, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Study: Low-dose CT scanning improves Ankylosing Spondylitis assessment A new study has shown that low-dose computed tomography (LD-CT) is more sensitive than X-rays for monitoring disease progression in people who have Ankylosing Spondylitis, according to a June 15 press release. LD-CT has previously been proven to be sensitive and reliable when assessing bone growth in different patients. The new study is designed to compare how well it can show the formation of new bony growth (syndesmophytes) and an increase in size in syndesmophytes. The study showed that LD-CT was more consistent when detecting these bone growths in AS patients than X-rays. About 30% of the patients in the study showed bony proliferation at three or more sites using LD-CT, while only 6% showed on conventional X-rays. The lead author was Dr. Anoek de Koning from the Leiden University Medical Centre in Leiden, Netherlands. 2. ConforMIS touts total knee replacement implant study ConforMIS announced in a June 13 press release announced study results for total knee arthroplasty (TKA) patients treated with customized individually made (CIM) implants or standard off-the-shelf (OTS) implants. There were 248 participants in the study. About 3.3% had events at discharge with...
Source: Mass Device - Category: Medical Devices Authors: Tags: Big Data Business/Financial News Cardiac Assist Devices Cardiovascular Clinical Trials Diagnostics Implants Oncology Research & Development Respiratory Cefaly conformis Consulting Radiologists Hemovent Image Stream Medical Me Source Type: news

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Authors: Yılmaz Susluer S, Kayabasi C, Ozmen Yelken B, Asik A, Celik D, Balci Okcanoglu T, Serin Senger S, Biray Avci C, Kose S, Gunduz C Abstract Long non-coding RNAs (lncRNAs) have been implicated in numerous biological processes, including epigenetic regulation, cell-cycle control, and transcriptional/translational regulation of gene expression. Differential expression of lncRNAs and disruption of the regulatory processes are recognized as critical steps in cancer development. The role of lncRNAs in hepatitis B virus (HBV) infection is not well understood. Here we analyzed the expression of 135 lncRNAs in plasm...
Source: Bosnian Journal of Basic Medical Sciences - Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
Authors: Guedes AF, Sargento L, Braz-Nogueira J, Lousada N, Moreira C, Carvalho FA, Santos NC Abstract Erythrocyte aggregation is an indicator of cardiovascular risk, which is influenced by plasma fibrinogen concentration. Fibrinogen levels are elevated during cardiovascular diseases. Our main goals were to understand how fibrinogen-erythrocyte binding influences erythrocyte aggregation and how it constitutes a cardiovascular risk factor in essential arterial hypertension (EAH) and chronic heart failure (CHF). Fibrinogen-erythrocyte and erythrocyte-erythrocyte adhesion measurements were conducted by atomic force mi...
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research
Abstract Objective: Fecal immunochemical tests (FITs) for hemoglobin in stool are increasingly used for colorectal cancer screening. Reported sensitivities and specificities have strongly varied between studies, but it is unclear to what extent such variation reflects differences between tests or between study population characteristics. We aimed to evaluate the key parameters of FIT performance for detecting advanced neoplasia (AN) according to sex and age. Methods: Sex- and age-specific sensitivity, specificity, positive predictive values (PPVs) and negative predictive values (NPVs) for detecting AN of a qu...
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: Clin Epidemiol Source Type: research
We read with great interest the recent article by Jonczyk et  al entitled “Diagnostic Accuracy of Split-Bolus Single-Phase Contrast-Enhanced Cone-Beam CT for the Detection of Liver Tumors before Transarterial Chemoembolization” (1). This retrospective single-center study showed how the use of cone-beam computed tomography (CT) as guidance for chemoemboli zation procedures led to 28.7% increased visualization of occult hypervascular nodules (121 vs 94 nodules compared with arterial phase magnetic resonance [MR] imaging) and roughly equal hypervascular nodule visualization rate compared with hepatobiliary phase MR imaging.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
We appreciate your interest in our recent publication concerning the split-bolus single-phase contrast-enhanced cone-beam computed tomography (CT) protocol for hypervascularized liver tumors (1). The diagnosis of hepatocellular carcinoma was verified in all cases before intervention with magnetic resonance (MR) imaging using imaging features such as the typical contrast enhancement patterns, including the hepatobiliary phase with liver-specific contrast agent and tumor growth at follow-up (2). However, some tumors failed to show a sharp arterial hyperperfusion and washout in the portal venous or venous phase, although tumo...
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
An 83-year-old man with bilateral common iliac artery aneurysms (right, 3.0 cm; left, 2.7 cm), bilateral internal iliac artery aneurysms (right, 3.4 cm; left, 2.6 cm), and an abdominal aortic aneurysm (3.8 cm) was treated with an aortobi-iliac stent graft and bilateral iliac branch devices. The internal iliac components were extended into opposing posterior (left) and anterior (right) divisions of the internal iliac artery using stent grafts. Computed tomography angiography demonstrated that all aneurysms decreased or were stable in size with patent stent grafts at 1 month.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Brief Report Source Type: research
A 27-year-old competitive runner presented with deep right thigh pain for 1  year. A T2-weighted hyperintense 3-cm lesion was found in the right vastus lateralis muscle on magnetic resonance imaging, indicative of a ganglion cyst (Fig 1). Corresponding ultrasound showed a well-defined, hypoechoic lesion confirming the diagnosis of ganglion cyst. This location is rare for g anglion cyst, and such lesions have been treated only by surgical excision. Ultrasound-guided aspiration and sclerosis with sodium tetradecyl sulfate was performed.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Images in IR Source Type: research
CONCLUSION: Client-centred occupational performance goals may be facilitated through placing goal-setting in the context of life changes and lifelong development of goals, and through listening to clients' stories. Therapists may improve consistency in adoption of client-suggested goals through clarifying meaning attached to goals and being attuned to power dynamics and underlying values and beliefs around risk and goal attainability. PMID: 29671662 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - Category: Occupational Health Tags: Scand J Occup Ther Source Type: research
CONCLUSION: The volume of fresh IPH is independently associated with MFCD in carotid plaques, suggesting that integrity of fibrous cap may change with different age and size of IPH. PMID: 29669957 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
CONCLUSION: TACE combined with partial hepatic segment thermal ablation is a safe and effective treatment for liver cancer patients, especially for those with more advanced disease. PMID: 29671661 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
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