7 medtech stories we missed this week: June 30, 2017
[Image from unsplash.com]From ConforMIS touting its knee replacement study to Consulting Radiologists’s new breast cancer detection tool, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Study: Low-dose CT scanning improves Ankylosing Spondylitis assessment A new study has shown that low-dose computed tomography (LD-CT) is more sensitive than X-rays for monitoring disease progression in people who have Ankylosing Spondylitis, according to a June 15 press release. LD-CT has previously been proven to be sensitive and reliable when assessing bone growth in different patients. The new study is designed to compare how well it can show the formation of new bony growth (syndesmophytes) and an increase in size in syndesmophytes. The study showed that LD-CT was more consistent when detecting these bone growths in AS patients than X-rays. About 30% of the patients in the study showed bony proliferation at three or more sites using LD-CT, while only 6% showed on conventional X-rays. The lead author was Dr. Anoek de Koning from the Leiden University Medical Centre in Leiden, Netherlands. 2. ConforMIS touts total knee replacement implant study ConforMIS announced in a June 13 press release announced study results for total knee arthroplasty (TKA) patients treated with customized individually made (CIM) implants or standard off-the-shelf (OTS) implants. There were 248 participants in the study. About 3.3% had events at discharge with...
Authors: Rankin KC, O'Brien LC, Gorgey AS Abstract OBJECTIVE: To determine whether dual energy x-ray absorptiometry (DXA) compared to magnetic resonance imaging (MRI) may accurately quantify trunk lean mass (LM) after chronic spinal cord injury (SCI) and to investigate the relationships between trunk LM, visceral adiposity, trunk fat mass and basal metabolic rate (BMR). DESIGN: Cross-sectional design and correlational analysis. SETTING: Research setting in a medical center. PARTICIPANTS: Twenty-two men with motor complete paraplegia (n = 14; T4-T11) and tetraplegia (n = 8; C5...
Abstract AimsNeoadjuvant chemotherapy (NAC) remains an important therapeutic option for advanced oesophageal cancer (OC). Pathological tumour regression grade (TRG) may offer additional information by directing adjuvant treatment and/or follow‐up but clinical value remains unclear. We analysed the prognostic value of TRG and associated pathological factors in OC patients enrolled in the Medical Research Council OE02 trial. MethodsHistopathology was reviewed in 497 resections from OE02 trial participants randomised to surgery (S‐group;n=244) or NAC followed by surgery (CS‐group;n=253). The association between TRG grou...
Conclusions:Results demonstrate that a BMI cut-point of 30 kg/m2 does not appear to be an appropriate indicator of true obesity status in postmenopausal women. Empirical estimates of the validity of BMI from this study may be used by other investigators to account for BMI-related misclassification in older women. Objective: Body mass index (BMI) is a widely used indicator of obesity status in clinical settings and population health research. However, there are concerns about the validity of BMI as a measure of obesity in postmenopausal women. Unlike BMI, which is an indirect measure of obesity and does not distinguis...
This Practice Pearl describes an approach to screening mammography for average-risk women that encourages the use of shared decision-making that addresses benefits (early diagnosis and decreased mortality) and potential harms (false positives and overdiagnosis/overtreatment) in determining screening mammography initiation, frequency, and duration for women at average risk of breast cancer.
In the current literature, there is limited evidence of benefit from survivorship care plans. Researchers are calling for a shift in the focus of current research.Medscape Medical News
ConclusionsRA patients had higher rates of HF and IHD throughout the entire observation period compared to the comparison cohort. RA was associated with a larger risk for developing HF.This article is protected by copyright. All rights reserved.
Conclusion: In this study, TARS followed by RAI therapy seems to be curative, even for patients with lymph node metastases, after good preoperative staging. More studies are required to confirm the findings.Eur Thyroid J
Na Kong, Mei Deng, Xiu-Na Sun, Yi-Ding Chen, Xin-Bing Sui
Hsiang-I Tsai, Lijuan Jiang, Xiaowei Zeng, Hongbo Chen, Zihuang Li, Wei Cheng, Jinxie Zhang, Jie Pan, Dong Wan, Li Gao, Zhenhua Xie, Laiqiang Huang, Lin Mei, Gan Liu
More than a third of patients with cancer of the esophagus responded to experimental treatment in China with the gene-editing technique CRISPR. Several CRISPR studies are underway there.(Image credit: Yuhan Xu/NPR)
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