Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study

Author Affiliations open 1MOE-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, USA 3Department of Neonatology, International Peace Maternal and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China PDF Version (161 KB) Abstract About This Article Supplemental Material Background: Triclosan (TCS) is a synthetic antibacterial chemical widely used in personal care products. TCS exposure has been associated with decreased thyroid hormone levels in animals, but human studies are scarce and controversial. Objective: We evaluated the association between maternal TCS exposure and thyroid hormone levels of mothers and newborns. Methods: TCS was measured by high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) in urine samples collected during gestational weeks 38.8±1.1 from 398 pregnant women in a prospective birth cohort enrolled in 2012–2013 in Shanghai, China. Maternal serum levels of free thyroxine (FT4), thyroid-stimulating hormone (TSH), and thyroid peroxidase antibody (TPOAb) were obtained from medical records. Cord blood levels of free triiodothyronine (FT3), FT4, TSH, and TPOAb were measured. Multiple linear and logistic regression models were used to examine the relationship between matern...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

Related Links:

The authors present a classroom activity designed to increase the motivation and confidence of Doctor of Pharmacy students in addressing the opioid crisis.American Journal of Pharmaceutical Education
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pharmacist Journal Article Source Type: news
India has once again topped an annual list of cities with the worst air quality in the world, according to a new report, while Chinese cities have continued to show improvements from the previous year.
Source: - Health - Category: Consumer Health News Source Type: news
San Antonio, Texas officials confirmed Monday that six American evacuees quarantined there - including one from Wuhan, China, and five from the Diamond Princess ship tested positive.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
[Capital FM] Nairobi -The Kenya Film Classification Board has appealed to media and entertainment stakeholders to ensure that children are protected from inappropriate content in their programs.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
China and South Korea have reported more cases of a new viral illness that has been concentrated in North Asia
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Basel, 25 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for the fixed-dose combination (FDC) of Perjeta® (pertuzumab) and Herceptin® (trastuzumab) with hyaluronidase, administered by subc utaneous (SC) injection in combination with intravenous (IV) chemotherapy, for the treatment of eligible patients with HER2-positive breast cancer. The BLA for the FDC is based on results from the phase III FeDeriCa study, which demonstrated non-inferior levels of Perjeta in the blood (phar...
Source: Roche Investor Update - Category: Pharmaceuticals Source Type: news
The Japanese government on Tuesday urged companies to recommend telecommuting and staggered shifts for workers in a bid to curb the spread of the new coronavirus.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
U.S. President Donald Trump will seek $2.5 billion from Congress to fight the coronavirus epidemic and U.S. and South Korean militaries are considering scaling back joint training as the virus spreads in Europe and the Middle East.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Japan's J.League says it has postponed seven Levian Cup matches scheduled for Wednesday due to concerns about the coronavirus outbreak and is considering postponing all domestic soccer games through the first half of March.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
The Supreme Court allowed the public charge rule to proceed and could permit Trump officials to bar immigrants without health insurance.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
More News: Alcoholism | Allergy | Allergy & Immunology | Brain | Canada Health | Cardiology | Cardiovascular | Chemistry | Child Development | Children | China Health | Denmark Health | Disability | Eating Disorders & Weight Management | Education | Endocrinology | Environmental Health | Epidemics | Epidemiology | Genetics | Germany Health | Grants | Health Management | Heart | Hormones | Hyperthyroidism | Hypothyroidism | International Medicine & Public Health | Japan Health | Laboratory Medicine | Liver | Netherlands Health | Neurology | Neuroscience | Norway Health | Obesity | OBGYN | Operative Vaginal Delivery | Perinatology & Neonatology | Pregnancy | Reproduction Medicine | Residencies | Science | Smokers | Statistics | Students | Study | Switzerland Health | Thyroid | Toxicology | Universities & Medical Training | Urology & Nephrology | USA Health | Weight Loss | WHO | Women