Evaluation of baseline frequency of sister chromatid exchanges in an italian population according to age, sex, smoking habits, and gene polymorphisms

ConclusionWe describe the association between some phase I, phase II, and DNA‐repair gene polymorphisms with increased SCEs frequencies, reinforcing the importance of genetic analysis in biomonitoring studies. Sex and age were found to be important endogenous factors that affect the level of genomic damage and the replicative capacity of cells, respectively.

Source: American Journal of Human Biology - May 6, 2017 Category: Biology Authors: Alfredo Santovito, Claudio Gendusa, Piero Cervella Tags: ORIGINAL RESEARCH ARTICLE Source Type: research