Reduced Lateral Prefrontal Cortical Volume is associated with Performance on the Modified Iowa Gambling Task: A Surface Based Morphometric Analysis of Previously Deployed Veterans with Post-traumatic Stress Disorder (PTSD), Mild Traumatic Brain Injury (mTBI), or Co-occurring PTSD/mTBI

Post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) are two of the most common consequences of combat deployment. Estimates of comorbidity of PTSD and mTBI are as high as 42% in combat exposed Operation Enduring Freedom, Operation Iraqi Freedom and Operation New Dawn (OEF/OIF/OND) Veterans. Combat deployed Veterans with PTSD and/or mTBI exhibit deficits in classic executive function (EF) tasks. Similarly, the extant neuroimaging literature consistently indicates abnormalities of the ventromedial prefrontal cortex (vmPFC) and amygdala/hippocampal complex in these individuals.

Source: Psychiatry Research: Neuroimaging - June 28, 2017 Category: Psychiatry Authors: Nicholas D. Fogleman, Farah Naaz, Lindsay K. Knight, Teodora Stoica, Samantha C. Patton, Jennifer H. Olson-Madden, Meghan. C. Barnhart, Trisha A. Hostetter, Jeri Forster, Lisa A. Brenner, Marie T. Banich, Brendan E. Depue Source Type: research