Cholesterol lowering treatment restores blood global DNA methylation in chronic kidney disease (CKD) patients

Chronic kidney disease (CKD) is characterized by increased oxidative stress (OS). In consideration of the well-known link between OS and DNA methylation we assessed DNA methylcytosine (mCyt) concentrations in CKD patients at baseline and during cholesterol lowering treatment.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - June 28, 2017 Category: Nutrition Authors: Angelo Zinellu, Salvatore Sotgia, Elisabetta Sotgiu, Stefano Assaretti, Angela Baralla, Arduino A. Mangoni, Andrea E. Satta, Ciriaco Carru Source Type: research