Two life-threatening conditions.One remarkable wish.
When Lucas St. Onge blew out the five candles on his birthday cake, he made just one wish. He didn’t ask for ninja turtles, a T-ball set or an Xbox — the only thing he wished was to be just like any other kid. “It was a gift I couldn’t give,” says his mom, Heather. On that same day, last May, he got his wish. “He got a liver, stomach, pancreas, intestine and spleen — the five organs he needed to help him become healthy and happy,” Heather says. Heather was 18 weeks pregnant when she and her husband, Anthony, learned they were about to face a myriad of medical challenges with their unborn child. To what extent remained unclear, until the day Lucas was born. An emergency surgery to repair multiple intestinal blockages left him with short bowel syndrome, or simply “short gut,” a rare condition caused by the loss of a functioning small intestine. It meant Lucas would never be able to eat or digest food. “I was told to take him home and to let him live out his days,” Heather says. “But I wasn’t willing to accept that.” Lucas was transferred to Boston Children’s Hospital for a second opinion. SCID and a bone marrow transplant Five days after arriving at Boston Children’s, the Immunology Program team diagnosed Lucas with severe combined immunodeficiency (SCID), a rare genetic condition in which a child’s immune system is so compromised that a common cold can kil...
(MedPage Today) -- Peter Ubel, MD, explains how to let older patients know tests won't help
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A preplanned analysis of ctDNA found that a subpopulation of mCRC patients with acquired anti-EGFR resistance were sensitive to treatment with Sym004.
The addition of metronomic chemotherapy to dual HER2 blockade improved outcomes in older and frail patients with HER2-positive metastatic breast cancer.
Date: Wednesday, 03 21, 2018; Speaker: Charles Rabkin, M.D., Senior Investigator, Division of Cancer Epidemiology and Genetics, NCI; https://epi.grants.cancer.gov/events
Date: Thursday, 03 29, 2018; Speaker: Cassandra Harris, M.S., M.C.H.E.S., Manager, Health Education, MD Anderson Cancer Center; Kathi Ridley-Merriweather, M.A., Communications and Minority Outreach Coordinator, Komen Tissue Bank; Ren é Arnold, M.B.A., Former Operations Manager, The Fountain of Praise Church; https://epi.grants.cancer.gov/events/enrich-forum/
The Wayne D. Kuni&Joan E. Kuni Foundation has awarded $5 million to Legacy Health Foundation to found a cancer research project. The grant will fund research into how cancer can be targeted by manipulating adenosine kinase, an enzyme that controls cell growth. The research is led by Detlev Boison, Dow Chair of Neurology and director of neurobiology research and basic and translational research at Legacy Research Institute; and Dr. Serene Perkins, director of surgical and clinical research at…
Conclusion: These findings demonstrate for the first time the molecular cascade and related cell biology events involved in the mechanism by which HGF and bFGF derived from hADSCs improved ovarian function during natural aging via reduction of oxidative stress by activating the SIRT1/FOXO1 signaling pathway.Cell Physiol Biochem 2018;45:1316 –1332
Cabozantinib showed significant antitumor activity in the treatment of differentiated thyroid cancer that progressed following surgery and radioactive iodine therapy, according to a new phase II study.
The head of the Kidney Foundation in Calgary says the family that put up billboards seeking donors is helping everyone waiting for a transplant.
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