UC biologist looks at butterflies to help solve human infertility

(University of Cincinnati) UC biologist helps decode the structural complexities of male butterfly ejaculate and co-evolving female reproductive tract. Findings from these biochemical relationships may help unlock certain mysteries of human infertility.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Comparing the role of anti-Müllerian hormone as a marker of FSH action in male and female fertility. Expert Rev Endocrinol Metab. 2019 Mar 04;:1-12 Authors: Urrutia M, Grinspon RP, Rey RA Abstract INTRODUCTION: Originally limited to the assessment of disorders of sex development, anti-Müllerian hormone (AMH) measurement has more recently been extended to several conditions affecting the reproductive axis in males and females. Follicle-stimulating hormone (FSH) regulation of gonadal function has been extensively studied, but its role on AMH production has been explored only recently. Areas cov...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Conditions:   Infertility;   Polyp Uterus;   Myoma;Uterus;   Adhesion;   Hysteroscopy;   Uterine Septum;   Retained Products of Conception Intervention:   Device: Hyalobarrier® gel endo Sponsors:   University Hospital, Ghent;   Belgium Health Care Knowledge Centre;   Nordic Pharma SAS;   Universitaire Ziekenhuizen Leuven;   Universitair Ziekenhuis Brussel;   Imelda Hospital, Bonheiden;   CTC BIMETRA;   University of L...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Fertility News - Doctors Lounge - Category: Reproduction Medicine Tags: Reproductive Medicine, Fertility, Research, News, Source Type: news
In conclusion, our results indicated that the IL-3 rs40401 polymorphism is associated with increased risk of abortion of IVF patients. Future studies with inclusion of other ethnic populations must be conducted to confirm the findings of this study.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
After an endometriosis diagnosis, Ash launched a program that matches individuals struggling with infertility with mentors who already had been through the process.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
ConclusionsThis study demonstrated that CFAP43 and CFAP44 mutations are important causes of MMAF in the Chinese population. These novel mutations broaden the spectrum of CFAP43 and CFAP44 mutations.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Publication date: Available online 16 March 2019Source: Reproductive BioMedicine OnlineAuthor(s): Kai J. Buhling, Annika Schumacher, Christine zu Eulenburg, Elena LaakmannAbstractTo study the evidence of the influence of micronutrient supplementation on male fertility based on published research and to make recommendations for micronutrient supplementation for men suffering from infertility.18 randomised, double-blind, placebo-controlled trials were included in the meta-analysis or in the systematic review.A significant improvement in semen parameters was evident for selenium (200 g orally, daily) and L-carnitine (LC; 2 g ...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
CONCLUSION: These results suggest that the polymorphism in MTHFD1 G1598A gene could be considered as an important genetic disorder associated with the etiology of male infertility. PMID: 30882176 [PubMed - as supplied by publisher]
Source: Urology Journal - Category: Urology & Nephrology Authors: Tags: Urol J Source Type: research
Abstract PURPOSE: The aim of this study was to evaluate expression of Post-Acrosomal WW Binding Protein (PAWP) in infertile men with low and high fertilization post ICSI and also globozoospermic men. MATERIALS AND METHODS: Semen samples were collected from 18 infertile men with previous failed or low fertilization (50%) post ICSI, 15 globozoospermic men, and 21 fertile individuals. Then, expression of PAWP was assessed at RNA with quantitative Real Time PCR. RESULTS: Relative expression of PAWP in sperm was significantly (p
Source: Urology Journal - Category: Urology & Nephrology Authors: Tags: Urol J Source Type: research
Genesis, genes and epigenetics of endometriosis-associated infertility, Published online: 18 March 2019; doi:10.1038/s41574-019-0191-9Jae-Wook Jeong and colleagues report that histone deacetylase 3 (HDAC3) is downregulated in the endometrium of women with endometriosis. In addition, they show that the loss of HDAC3 is associated with aberrant hormonal signalling and increased fibrosis in the endometrium and impaired endometrial receptivity.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research
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