Consider Acupuncture for Incontinence, But Not Infertility Due To PCOS
TUESDAY, June 27, 2017 -- Acupuncture, a 3,000-year-old healing technique, received mixed reviews in two new studies from China -- one focusing on incontinence and the other on a cause of female infertility. A research team found acupuncture did...
Publication date: Available online 23 June 2018 Source:Journal of Acupuncture and Meridian Studies Author(s): Cássia Maria Grillo, Vera Lúcia Rasera Zotelli, Maria Lúcia Bressiani Gil, Maria da Luz Rosário de Sousa
CONCLUSION: First line management of infertility once a diagnosis of PCOS is made should include weight loss and exercise with goals to below class 2 obesity (BMI
CONCLUSIONS Women with PCOS who underwent IVF, oral treatment with letrozole a day prior to treatment with hCG lowered E2 levels, but did not significantly reduce the incidence of OHSS. PMID: 29925074 [PubMed - in process]
In this study we report on the investigation of complete infertility in a 5-year-old Thoroughbred stallion. The stallion was considered infertile after performing 72 covers and achieving 0 pregnancies over one breeding season. Although initial semen assessment (sperm concentration, motility, longevity and morphology) revealed below average parameters, these were not sufficient to explain complete infertility under a managed system. The stallion displayed normal libido, breeding behavior and ejaculation, and semen contained viable, progressively motile spermatozoa (number of total progressively motile sperm per ejaculate ra...
Seminal vesiculitis is one of the causes of pyospermia affecting the fertility of stallions. To date, recommended treatments have variable results and reoccurrence is a common sequela. The development of management tools for stallions affected is warranted. Thus, the objective of this study was to evaluate fractionated semen collection as a method to rescue fertility of stallions diagnosed with seminal vesiculitis. The study was performed from April of 2014 to October of 2017 with six light-breed stallions with a history of infertility and pyospermia.
The imbalance between reactive oxygen species (ROS) generation and antioxidant defensive mechanisms results in excessive ROS levels that promote sperm DNA fragmentation, mitochondrial dysfunction and membrane lipid peroxidation, which are associated with infertility. Curcumin (CUR, Curcuma longa) is a natural phytochemical compound of turmeric that exhibits antioxidant properties. CUR can have beneficial effect on sperm motility by increasing antioxidant mechanisms and controlling lipid peroxidation and nitric oxide production.
Low levels of intracellular reactive oxygen species (ROS) are essential for normal spermatozoal function and are produced by sperm mitochondria as a byproduct of metabolism, but in excess, ROS can cause catastrophic cellular damage and has been correlated with infertility, poor sperm motility and abnormal morphologies in humans (Aziz et. al. Fertility and Sterility. 2004; 2: 349-354). Stallion sperm fuel motility predominantly by oxidative phosphorylation-produced ATP, requiring high basal rates of mitochondrial function.
While it is well established that mammalian male fertility has a genetic component, genomics tools for evaluating fertility in stallions are limited. The Y chromosome is enriched with genes important for spermatogenesis and sperm functions as evidenced by human and mouse studies showing causative links between Y chromosome rearrangements, mutations, copy number variants (CNVs) and various male infertility phenotypes; hence, Y chromosome studies were initiated in the horse. We recently produced a 9.5 Mb annotated reference sequence for the male specific region of the horse Y (MSY).
Granulosa cell tumours (GCT) are the most common tumor which affect ovarian tissue in mares. Mares with GCT may become infertile due to the suppressed activity of the contralateral normal ovary, and if GCT are ablated by surgery, the normal ovary will become active, with recovery from infertility .
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Two new trials in JAMA report mixed findings for acupuncture: One shows that acupuncture may help treat stress urinary incontinence, while the other shows no effect on infertility …