Early insights into Zika's microcephaly physiopathology, from the epicentre of the outbreak: teratogenic apoptosis on the central nervous system

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Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Commentary Source Type: research

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Abstract During the 2016 Zika pandemic in Brazil, women's perceptions of infection risk, ability to adhere to Zika prevention strategies, or access to services following exposure were not emphasized in the public health response. Women in Fortaleza, Brazil, responded to a questionnaire on social factors related to perceived Zika risk and access to health care in June 2016. Data were coded using prespecified categories, and response frequency was reported. Of 37 respondents, most reported a lack of public services to support mosquito control (n = 19) or delayed access to reproductive health care (n = 14). Only 22% ...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
This article analyzes the possible causes of ZIKV virus outbreaks from the perspective of genetic evolution and analyzes the dynamic trends of virus outbreaks to provide a theoretical basis for predicting the outbreak of the virus.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
A study of cases from a 2016 outbreak in Florida provides insight into Zika virus IgM persistence.Emerging Infectious Diseases
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Researchers at Penn State have developed a handheld device called VIRRION that can capture and identify viral particles in samples within minutes. The device contains a “forest” of carbon nanotubes that capture and sort viral particles de...
Source: Medgadget - Category: Medical Devices Authors: Tags: Pathology Public Health Source Type: blogs
In the United States, more than 7400 pregnancies with laboratory evidence of confirmed or possible Zika virus infection were identified and included in the national surveillance network, the US Zika Pregnancy and Infant Registry, during the Zika virus outbreak in the Region of the Americas from 2015 to 2017. These pregnancies included those completed from December 1, 2015, through March 31, 2018, meaning the children from these pregnancies ranged in age from 18 months to nearly 4 years by the fall of 2019. Although between 5% and 10% of these children have received a diagnosis of serious defects of the brain or eye, includ...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
ConclusionsThe paper describes a strategy that applies newspaper as proxies to monitor outbreaks of infectious diseases and to study the epidemiology. It has potential applicability in some developing countries and regions with relatively poor medical infrastructures and records. Clearly, large national newspapers in India provide a better source of information on diseases than international outlets. This approach has potential with selected diseases in a few selected countries. Article numbers internationally appear to vary in proportion to the perceived health impact.Graphical abstract
Source: Journal of Biomedical Informatics - Category: Information Technology Source Type: research
CONCLUSIONS: The results indicate climate zone to be an important determinant of the basic reproduction number, R0, for dengue, Zika virus, and chikungunya. The role of other factors as determinants of R0, such as methods, environmental and social conditions, and disease control, should be further investigated. The results suggest that R0 may increase in temperate regions in response to global warming, and highlight the increasing need for strengthening preparedness and control activities. PMID: 31927301 [PubMed - as supplied by publisher]
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
Publication date: Available online 28 December 2019Source: Biosensors and BioelectronicsAuthor(s): Bhagwan S. Batule, Youngung Seok, Min-Gon KimAbstractThe recent outbreaks of mosquito-borne diseases (e.g., zika, dengue, and chikungunya) increased public health burden in developing countries. To control the spread of these infectious diseases, a simple, economic, reliable, sensitive, and selective diagnostic platform is required. Considering demand for affordable and accessible methods, we have demonstrated a two-step strategy for extraction and detection of viral RNAs of infectious diseases within 1 h. Ready-to-use devi...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
by Michel J. Counotte, Christian L. Althaus, Nicola Low, Julien Riou The 2015–2017 epidemics of Zika virus (ZIKV) in the Americas caused widespread infection, followed by protective immunity. The timing and burden of the next Zika virus outbreak remains unclear. We used an agent-based model to simulate the dynamics of age-specific immunity to ZIKV, and predict th e future age-specific risk using data from Managua, Nicaragua. We also investigated the potential impact of a ZIKV vaccine. Assuming lifelong immunity, the risk of a ZIKV outbreak will remain low until 2035 and rise above 50% in 2047. The imbalance in age-s...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Publication date: Available online 16 December 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Sibel Ciftci, Felix Neumann, Samir Abdurahman, K. Sofia Appelberg, Ali Mirazimi, Mats Nilsson, Narayanan MadaboosiEmerging tropical viruses have caused serious outbreaks during the recent years, such as Ebola virus (EBOV) in 2014 and the most recent in 2018 to 2019 in Congo. Thus, immediate diagnostic attention is demanded at the point of care in resource-limited settings, because the performance and the operational parameters of conventional EBOV testing are limited. Especially, their sensitivity, specificity, and cov...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
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