Biochemical Effects of the Aqueous Extract of Hibiscus sabdariffa on Liver Marker Enzymes and Lipid Profiles in Acetaminophen-challenged Rats

This study was conducted to determine the hepato-regenerative properties of aqueous extract of Hibiscus sabdariffa leaves in acetaminophen induction of the liver by using rat model. Materials and Methods: Twenty Wistar Albino rats were used for this study and were divided into four groups. Group 1 rats were normal control group 2 (positive control) rats were administered acetaminophen only at a dose of 750 mg kg–1 b.wt., i.p. Both rats of group 3 and 4 were administered low and high doses respectively at 600 mg kg–1 b.wt., of the extract after induction of acetaminophen. The results were analyzed using one way analysis of variance using SPSS version 20. Results: Group 2 rats treated with acetaminophen only showed significant increase (p
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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Publication date: Available online 15 August 2018Source: SteroidsAuthor(s): Julius Fink, Masahito Matsumoto, Yoshifumi TamuraAbstractSedentary lifestyle and over-nutrition are the main causes of obesity and type 2 diabetes (T2D). However, the same causes are major triggers of hypogonadism. Many T2D patients show low testosterone levels while hypogonadal men seem to be prone to become diabetic. Testosterone plays a major role in the regulation of muscle mass, adipose tissue, inflammation and insulin sensitivity and is therefore indirectly regulating several metabolic pathways, while T2D is commonly triggered by insulin resi...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
In conclusion, it remains unclear whether AD is a risk factor for metabolic syndrome and its components. However, data indicate that central obesity is associated with AD and that the association is stronger for women than men.Dermatology
Source: Dermatology - Category: Dermatology Source Type: research
A growing number of studies suggest that getting a handle on a few key risk factors can bring type 2 diabetes under control. Lowering blood sugar, for instance, reduces the risk of additional health problems, such as heart disease and stroke related to the disease. But most of these studies have focused on studying one risk factor — like blood sugar, cholesterol or blood pressure — at a time. In a new study published in the New England Journal of Medicine, researchers analyzed what happens to death rates and other health problems when people control up to five known risk factors for type 2 diabetes. The study ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime medicine Source Type: news
Overweight people who lost 5 to 10 percent of their weight lowered their risk for metabolic syndrome by 22 percent. Those who lost 20 percent cut their risk by over 50 percent.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Obesity Weight Diet and Nutrition Cholesterol Blood Pressure Source Type: news
Publication date: Available online 15 August 2018Source: Food Research InternationalAuthor(s): Whyara Karoline Almeida da Costa, Larissa Ramalho Brandão, Maria Elena Martino, Estefânia Fernandes Garcia, Adriano Francisco Alves, Evandro Leite de Souza, Jailane de Souza Aquino, Maria Saarela, François Leulier, Hubert Vidal, Marciane MagnaniAbstractTropical fruit and their industrial processing byproducts have been considered sources of probiotic Lactobacillus. Sixteen tropical fruit-derived Lactobacillus strains were assessed for growth-promoting effects using a host-commensal nutrient scarcity model with...
Source: Food Research International - Category: Food Science Source Type: research
Oatmeal is a near-universally beloved breakfast. While it has historically been enjoyed across Europe, Russia and the U.S., oatmeal is rapidly gaining popularity in developing countries because of its affordability and its perceived health properties. But is oatmeal really good for you? To answer that question, it’s first important to differentiate among all the different types of oatmeal. There’s steel-cut and rolled, quick-cooking and instant. But all of these terms refer to different methods of preparing hulled oats for cooking. “You can’t eat an unprocessed oat straight from the field,” sa...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime Source Type: news
As part of the Norwegian government’s budget for 2018, the Parliament (“Storting”) introduced a new program called Medicine Start that aims to ensure the safe use of drugs for patients with chronic diseases. The program started in 2018, offering patients with cardiovascular diseases consultations with local pharmacists regarding their treatment with antihypertensive, cholesterol-lowering, or blood-thinning medications.        
Source: The Commonwealth Fund: Publications - Category: International Medicine & Public Health Source Type: research
Conditions:   Hypercholesterolemia;   Cognitive Dysfunction;   Hyperhomocysteinemia Intervention:   Diagnostic Test: Blood sampling for total cholesterol and homocysteine and cognitive assessment by psychometric tests. Sponsor:   Assiut University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsAlthough these results suggest that control of inflammation could have a beneficial effect on the lipid profile through an increase in HDL cholesterol levels, the observed protective effect on cardiovascular disease events by tumor necrosis factor blockers is likely to be explained by other mechanisms than changes in lipid levels or short-term effects on atherosclerosis of the carotid artery.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
The present study provides actual data with regard to the prevalence of myocardial ischemia among patients under contemporary cardiovascular prevention strategies undergoing peripheral vascular interventions. We included a total of 200 consecutive patients who underwent gated single-photon emission computed tomography myocardial perfusion study between January 2012 and January 2014 as preoperative evaluation for peripheral vascular interventions at our institution. The baseline medical treatment comprised aspirin (81%), statins (79%), and β-blockers (54%). Thirty-two (16%) patients underwent carotid revascularization;...
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
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