Up in the Air: Does Ground-Level Ozone Trigger Kawasaki Disease?

PDF Version (455 KB) About This Article Published: 23 June 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000–2010) Chau-Ren Jung, Wei-Ting Chen, Yu-Ting Lin, and Bing-Fang Hwang Kawasaki disease occurs most often in children of East Asian ancestry,1 but the known genetic factors2 cannot explain why more children have been diagnosed with the disease in recent years, according to Bing-Fang Hwang, an environmental epidemiologist at China Medical University in Taiwan. Hwang and colleagues now report an association between exposure to ground-level ozone and increased risk of Kawasaki disease in a group of young Taiwanese children.3 Kawasaki disease is a childhood ailment that causes fever, rash, and a red tongue, among other symptoms. It leads to inflammation in blood vessels throughout the child’s body. Most children recover from the disease within a few weeks, but up to one-qu...
Source: EHP Research - Category: Environmental Health Authors: Tags: Science Selections Source Type: research

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Authors: Shi R, Luo Y, Li S, Kong M, Liu X, Yu M, Wu J, Huang L, Yang Z Abstract Background: Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. Cyclophilin A (CypA), also known as PPIA, has been identified to play a vital role in the pathogenesis of cardiovascular or inflammatory diseases. However, no studies have examined the relationship between single-nucleotide polymorphisms (SNPs) in the peptidylprolyl isomerase A (PPIA) and the development of KD and KD with or without coronary artery lesions (CALs).Objective: The present study was conducted to evaluate whether PPIA SNPs are associated ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Publication date: February 2020Source: Alter, Volume 14, Issue 1Author(s):
Source: ALTER - European Journal of Disability Research - Category: Disability Source Type: research
The objective of this work was to study hydrogel dressings containing AgNPs from silver nitrate, synthesized by radiation involving the formation of silver nanoparticles with simultaneous occurrence of crosslinking and sterilization of the polymer systems. One of the hydrogels was prepared with poly(N-vinyl-2- pyrrolidone) (PVP) and the other with poly(vinyl alcohol) (PVA) as main studied polymers. An aqueous solution of AgNO3 was added to both polymer systems separately. The AgNPs synthesis, polymer crosslinking and dressing sterilization were achieved simultaneously by irradiating the resultant solutions with gamma-rays ...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Authors: Aresta C, Passeri E, Corbetta S Abstract Current primary hyperparathyroidism (PHPT) clinical presentation is asymptomatic in more than 90% of patients, while symptoms concern osteoporosis and rarely kidney stones. Here, we retrospectively investigated the prevalence of PHPT patients presenting with hypercalcemic-related symptoms (HS-PHPT) as cognitive impairment, changes in sensorium, proximal muscle weakness, nausea and vomiting, constipation, and severe dehydration, in a single center equipped with an emergency department and described their clinical features and outcome in comparison with a series of as...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Abstract Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. The disease affects more women than men and often is diagnosed during a woman's childbearing years. Typical clinical presentations of the disease are extensive and variable, with symptoms that include dysregulated mood, fatigue, vision problems, weakness, tremor, imbalance, abnormal sensations, bladder dysfunction, and heat sensitivity. If a woman aged 15-50 years experiences these neurologic symptoms in isolation or combination, and the symptoms are not explained by other underlying medical conditio...
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
We report a case of migration of arterial stent, placed in the right iliac vein into the right pulmonary artery which was diagnosed there and subsequently not removed for at least 3 years. Despite reports in the literature for the removal of migrated stents by mini-invasive interventional methods, in our case, this was not possible, because of the long period for which the foreign body was in the right pulmonary artery and the proximal partial occlusion of organized mural thrombus.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Authors: De Vecchis R, Paccone A, Di Maio M Abstract INTRODUCTION: The guidelines of the Scientific Societies of Cardiology suggest limiting water intake in the diet as one of the non-pharmacological measures for the management of chronic heart failure. However, many patients with heart failure may suffer from severe thirst, even irrespective of a possible restricted fluid intake, and this has received relatively little attention in clinical studies. Moreover, definitive and irrefutable evidence that documents the efficacy of the limitation in water consumption on major cardiovascular outcomes is lacking. Therefore...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
CONCLUSIONS: Not all interventional procedures result in a mortality benefit. Medical therapy alone increases survival in many cardiac diseases. PMID: 32083425 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: Guillaume GM, Vuylsteke ME, Dalcq V, Van der Borght L, Meeus P, de Maeseneer MG Abstract BACKGROUND: To date, it is unclear how treatment of patients with chronic venous disease (CVD) is influenced by national reimbursement systems. In Belgium, catheters or fibers used for endovenous thermal ablation (EVTA) are reimbursed only once in a lifetime. The potential impact of the Belgian public health insurance reimbursement policy on surgical practice in phlebology needs to be investigated. METHODS: Billing data available from the Belgian National Institute for Health and Disability Insurance (NIHDI) were u...
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
Exploring unusual subjects, from autopsies to the minutiae of long-haul truckingMortem |BBC SoundsOver the Road |radiotopia.fmThe Space Programme |funkidslive.comAn intriguing new series on BBC Sounds, made by the always reliable Whistledown Productions, has a mortician,Carla Valentine, talk us through her job. But this show isn ’t just about cutting and shutting. Valentine also introduces us to other non-police experts performing seemingly small procedures when confronted with a suspicious death. For instance: a man is found burned to death in a wood. Was it suicide or murder? What can the body reveal? What about th...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Radio Podcasts Science Space Beastie Boys Alan Partridge Nora Ephron Culture Source Type: news
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