Long ‐term outcome of anorexia nervosa: Results from a large clinical longitudinal study

DiscussionMany patients with very severe AN recover from their illness but AN also shows considerable long‐term negative consequences. Over long time periods, survivors show improvement but better treatments for severe cases are still needed. Predictors of outcome included symptom severity, chronicity, and length of follow‐up but not psychiatric comorbidity.
Source: International Journal of Eating Disorders - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Authors: Lammers WJ, van Tilburg AJ, Apers JA, Wiebolt J Abstract Bariatric surgery is an effective tool in the treatment of patients with morbid obesity. In these case reports we describe 2 patients who developed liver failure after currently-practiced types of bariatric surgery, caused by a prolonged state of malnutrition provoked by psychiatric problems. Despite intensive guidance of a psychologist and dieticians after surgery, our patients deteriorated psychologically, resulting in a prolonged state of severe malnutrition and anorexia. Finally, a state of starvation was reached, passing a critical level of the ...
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
John R. Speakman Human obesity has a large genetic component, yet has many serious negative consequences. How this state of affairs has evolved has generated wide debate. The thrifty gene hypothesis was the first attempt to explain obesity as a consequence of adaptive responses to an ancient environment that in modern society become disadvantageous. The idea is that genes (or more precisely, alleles) predisposing to obesity may have been selected for by repeated exposure to famines. However, this idea has many flaws: for instance, selection of the supposed magnitude over the duration of human evolution would fix any thrif...
Source: Journal of Experimental Biology - Category: Biology Authors: Tags: REVIEW Source Type: research
Here’s how to take that first small step. Food addiction is real. And if you’re struggling with food addiction, know that you’re not alone — I’ve been there, too. In fact, the younger you are, the more likely it’s your struggle. From my past experience as a compulsive overeater, I suspect that many food addictions act as pacifiers for pain, fears, and anxieties, and even as ways to celebrate emotional spikes that are positive. Food seems to act as a life enhancer, while offering the illusion of short-term emotional balance. As a food addict, you’ve established neural pathways and a...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Eating Disorders Exercise & Fitness Health-related Personal Publishers YourTango Binge Eating Compulsion Food Addiction Healthy Eating obese overeating Overweight Weight Gain Source Type: blogs
Conditions:   Anorexia;   Obesity;   Smoking Cessation Interventions:   Behavioral: Ads display with target websites;   Behavioral: Ads display with control websites Sponsors:   Microsoft Research;   Schneider Children's Medical Center, Israel;   Interdisciplinary Center (IDC) Herzeliya Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract ObjectiveKnowledge about physical fitness in women with bulimia nervosa (BN) or binge‐eating disorder (BED) is sparse. Previous studies have measured physical activity largely through self‐report, and physical fitness variables are mainly restricted to body mass index (BMI) and bone mineral density. We expanded the current knowledge in these groups by including a wider range of physical fitness indicators and objective measures of physical activity, assessed the influence of a history of anorexia nervosa (AN), and evaluated predictive variables for physical fitness. MethodPhysical activity, blood pressure, car...
Source: International Journal of Eating Disorders - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract ObjectiveWe investigated the presence of disordered eating attitudes and weight perception among young women at body mass index (BMI) values that correspond to underweight, normal weight, overweight, and obese weight status. MethodData were collected from 1,147 female undergraduate students (89% Kuwaiti nationals) recruited from Kuwait University through employment of the eating attitude test (EAT‐26) together with an anonymous, self‐administered questionnaire to determine the prevalence of symptomatology indicative of anorexia nervosa and bulimia nervosa. ResultsThe mean EAT‐26 scores differed significantly...
Source: International Journal of Eating Disorders - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract BACKGROUND: The role of the gut microbiota in Anorexia nervosa (AN) has long been neglected by researchers, although the former is known to play an important role in health, disease and weight regulation. Overweight and underweight due to natural states of starvation and refeeding are normal in many vertebrates in their ecological niches. OBJECTIVE: The aim of this review was to compare the similarities and differences between the gut microbiota in eating disorders with conditions of fasting and refeeding in other vertebrates. METHOD: A systematic literature search was conducted in Pubmed and We...
Source: Current Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Neuropharmacol Source Type: research
Publication date: Available online 8 January 2018 Source:Chemico-Biological Interactions Author(s): Vishal Patel, Amit Joharapurkar, Samadhan Kshirsagar, Brijesh Sutariya, Maulik Patel, Dhreerendra Pandey, Hiren Patel, Ramchandra Ranvir, Shekhar Kadam, Dipam Patel, Rajesh Bahekar, Mukul Jain Dyslipidemia enhances progression of atherosclerosis. Coagonist of GLP-1 and glucagon are under clinical investigation for the treatment of obesity and diabetes. Earlier, we have observed that coagonist reduced circulating and hepatic lipids, independent of its anorexic effects. Here, we investigated the role of coagonist of GLP-1 and...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Abstract Dyslipidemia enhances progression of atherosclerosis. Coagonist of GLP-1 and glucagon are under clinical investigation for the treatment of obesity and diabetes. Earlier, we have observed that coagonist reduced circulating and hepatic lipids, independent of its anorexic effects. Here, we investigated the role of coagonist of GLP-1 and glucagon receptors in complications of diet-induced dyslipidemia in hamsters and humanized double transgenic mice. Hamsters fed on high fat high cholesterol diet were treated for 8 weeks with coagonist of GLP-1 and glucagon receptors (75 and 150 μg/kg). Pair-fed control...
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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