Marked regional endothelial dysfunction in mottled skin area in patients with severe infections

Mottling around the knee, reflecting a reduced skin blood flow, is predictive of mortality in patients with septic shock. However, the causative pathophysiology of mottling remains unknown. We hypothesized tha...

Source: Critical Care - June 23, 2017 Category: Intensive Care Authors: Simon Bourcier, J érémie Joffre, Vincent Dubée, Gabriel Preda, Jean-Luc Baudel, Naïke Bigé, Guillaume Leblanc, Bernard I. Levy, Bertrand Guidet, Eric Maury and Hafid Ait-Oufella Source Type: research