Correspondence HPV control and resistance in the Middle East and north Africa
We thank Murat G ültekin and Baki Akgül,1 and we agree wholeheartedly with the fact that Islamic countries, and countries with more conservative sexual views based on religion in general, should implement educational projects in government-organised programmes. As we mentioned in our original Correspondence,2 the organisation of intervention policies based on awareness campaigns can be a very effective first step in the control of cervical cancer caused by HPV. However, a point that we would like to stress once more is that acceptance and implementation of these programmes, and in effect also vaccines, can b e faced with difficulties because of stigmatisation that is based on religious and traditional values.
Conclusions: A physician’s recommendation should advise AA mothers on the risk of HPV and the importance of HPV vaccination at an early age to reduce cervical cancer risk. It should further address mothers’ perceived disadvantages of HPV vaccination (eg, side effects). Incorporating this information in physician recommendation practices could increase HPV vaccination rates with implications in reducing the cervical cancer burden among this high-risk population.
In conclusion, the generated data will be highly beneficial for developing molecular diagnostic tools, analyzing and correlating the epidemiological data to determine the risk of cervical cancer and finally to develop a vaccine for Saudi Arabian population.
Publication date: June 2018Source: Sexual &Reproductive Healthcare, Volume 16Author(s): Gorica Marić, Đurđa Birčanin, Vesna Kisić, Jelena Dotlić, Milica Zarić, Darija Kisić-Tepavčević, Tatjana GazibaraAbstractStudy objectiveAssessing knowledge and attitudes of parents towards human papillomavirus (HPV) vaccination of their children and estimating factors associated with parental positive attitude towards HPV immunization.Study designCross-sectional.SettingTwo Community Health Centers. A total of 282 adult parents of boys and/or girls who presented at the pediatrician’s office with their child aged ≤1...
ConclusionsA significant decrease in the incidence of cervical cancer among young females after the introduction of human papillomavirus vaccine may indicate early effects of human papillomavirus vaccination.
ConclusionsDiagnosis of CIN2+ decreased in women aged 18–24 years, but not in older women. Both changes in screening and human papillomavirus vaccination could have contributed to the decline of CIN2+ in young women.
Publication date: July 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 1Author(s): Glen B. Taksler, Elizabeth R. Pfoh, Kurt C. Stange, Michael B. RothbergIntroductionThe number of preventive care guidelines is rapidly increasing. It is unknown whether the number of guideline-recommended preventive services is associated with utilization.MethodsThe authors used Poisson regression of 390,778 person-years of electronic medical records data from 2008 to 2015, in 80,773 individuals aged 50–75 years. Analyses considered eligibility for 11 preventive services most closely associated with guidelines: to...
ConclusionPacific Islanders referred to TAMC present with a disproportionally higher rate of regional and advanced disease. Significantly, only 28% of invasive cervical cancers in the Pacific Island population sampled could have been potentially be prevented using the available quadrivalent vaccine targeting HPV 16/18; however, 88% could be covered by the recently licensed nonavalent vaccine.
Publication date: Available online 26 April 2018Source: Reports of Practical Oncology &RadiotherapyAuthor(s): Mireia Diaz, Silvia de Sanjosé, F. Xavier Bosch, Laia BruniAbstractSimulation models are commonly used to address important health policy issues that cannot be explored through experimental studies. These models are especially useful to determine a set of strategies that result in a good value for money (cost-effectiveness). Several mathematical models simulating the natural history of HPV and related diseases, especially cervical cancer, have been developed to calculate a relative effectiveness and cost...
CONCLUSION: Most vulvar and vaginal lesions were attributable to at least 1 of the 14 HPV genotypes analyzed. Effective immunization programs could potentially prevent substantial numbers of HPV-related vulvar and vaginal LSILs and HSILs. CLINICAL TRIAL REGISTRATION: CLINICALTRIALS.GOV,: NCT00092521 and NCT00092534. PMID: 29995724 [PubMed - as supplied by publisher]