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Correspondence Guillain-Barr é syndrome and arboviral infection in Brazil

Among the clinical manifestations associated with the recent Zika infection outbreak in South America and elsewhere are rash, conjunctivitis, Guillain-Barr é syndrome (GBS) in exposed adults, and in the newborn so-called congenital Zika syndrome, especially microcephaly.1 After accumulating epidemiological data from the French Polynesia2 outbreak, attention has now focused on Zika infection as a trigger of GBS. The case for a specific, causal associat ion between acute Zika infection and subsequent GBS was strongly made: 42 individuals were diagnosed with GBS, of whom all had Zika neutralising antibodies.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research

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Abstract Zika Virus (ZIKV), originally identified in 1947, is a re-emerging Flavivirus transmitted mainly through bites by Aedes mosquitos. Until the recent outbreaks in the Pacific islands and Central and South America, it was known to cause benign disease, in most cases asymptomatic or with mild and nonspecific symptoms (fever, rash, conjunctivitis, arthralgia, etc.). The unprecedented current epidemic has highlighted new modes of transmission (through blood, perinatally and sexually) as well as serious neurological complications such as congenital defects in the fetuses of infected mothers and Guillain-Barre sy...
Source: Annales de Dermatologie et de Cenereologie - Category: Dermatology Authors: Tags: Ann Dermatol Venereol Source Type: research
We report the results of a rapid assessment of Zika virus awareness among key clinical specialties in Singapore, with the aim of identifying gaps in knowledge and opportunities for improving communication on Zika virus disease management and control policies. Methods Study Participants and Sites Between June 6 and June 19, 2016 prior to the Zika virus outbreak, we conducted an online survey of doctors working in obstetrics and gynaecology, neonatology and paediatrics in Singapore. A link to the online survey was disseminated by email to the relevant doctors at KK women’s and Children’s Hospital and Singapo...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
Abstract The Zika virus is a positive sense, single-stranded RNA arbovirus in the Flaviviridae family, genus Flavivirus. This virus was initially isolated in Africa and is transmitted to nonhuman primates and humans by mosquitoes. Initial reports describe sporadic mild viral infection with fever, arthralgia, myalgia and conjunctivitis in Africa and Asia. However, its geographic distribution has significantly increased, and it has caused large outbreaks in the Yap Islands in 2007, in French Polynesia in 2013 and in Brazil in 2015. Multiple cases of Guillain-Barre´ syndrome occurred in French Polynesia and Col...
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Tags: Am J Med Sci Source Type: research
Zika virus has been a recent international public health concern with outbreaks occurring in the Americas, Caribbean, and Pacific. The zoonotic infection is primarily spread to humans by the bite of an infected Aedes mosquito. The virus also can be transmitted via bodily fluids, sexual intercourse, and maternal-fetal vertical transmission. Asymptomatic presentation is common. If symptoms do occur, individuals display a low-grade fever, maculopapular rash, arthralgia, or conjunctivitis 2 to 7 d after infection. Infection is concerning due to its associated fetal effects in pregnant women and relationship with Guillain-Barre...
Source: Current Sports Medicine Reports - Category: Sports Medicine Tags: Environmental Conditions: Section Articles Source Type: research
Abstract Zika virus has been a recent international public health concern with outbreaks occurring in the Americas, Caribbean, and Pacific. The zoonotic infection is primarily spread to humans by the bite of an infected Aedes mosquito. The virus also can be transmitted via bodily fluids, sexual intercourse, and maternal-fetal vertical transmission. Asymptomatic presentation is common. If symptoms do occur, individuals display a low-grade fever, maculopapular rash, arthralgia, or conjunctivitis 2 to 7 d after infection. Infection is concerning due to its associated fetal effects in pregnant women and relationship w...
Source: Current Sports Medicine Reports - Category: Sports Medicine Authors: Tags: Curr Sports Med Rep Source Type: research
Zika virus is a single-stranded RNA virus (genus Flavivirus) transmitted by the Aedes mosquito and through sexual contact with infected individuals.1,2 Zika virus infection may be asymptomatic or may cause fever, rash, joint pain, conjunctivitis, myalgias, and headache.1 Initially endemic to Africa and Asia, outbreaks in the Pacific Islands occurred in 2007 and 2013, and Central America, South America, and the Caribbean islands are currently in the midst of an epidemic. In both prior and current outbreaks of Zika,1 an increased incidence of Guillain-Barré syndrome (GBS) has been reported.
Source: Neurology - Category: Neurology Authors: Tags: All Infections, Guillain-Barre syndrome CLINICAL/SCIENTIFIC NOTES Source Type: research
Authors: Şahiner F Abstract Zika virus (ZIKV) is an enveloped RNA virus that belongs to the Flaviviridae family. Although more than 60 years have passed since the discovery and first reported human cases of the virus, only a small number (
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
This report provides an update to the epidemiology of and public health response to ongoing Zika virus transmission in Puerto Rico. During November 1, 2015-April 14, 2016, a total of 6,157 specimens from suspected Zika virus-infected patients were evaluated by the Puerto Rico Department of Health (PRDH) and CDC Dengue Branch (which is located in San Juan, Puerto Rico), and 683 (11%) had laboratory evidence of current or recent Zika virus infection by one or more tests: reverse transcription-polymerase chain reaction (RT-PCR) or immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA). Zika virus-infected patients r...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
CONCLUSIONS ZIKV epidemic poses new challenges to public health, our knowledge about this virus is incipient. In Brazil, a relationship between ZIKV and microcephaly has been mentioned since November 20157 which has not been reported in ZIKV outbreaks in other areas of the world. Several research groups are working on this topic. Guillain Barré Syndrome also has been reported as a complication of ZIKV; however, there are still many questions unanswered regarding the complications caused by this virus. Provide information to the population, following recommendations and preventive measures, taking actions to reduce...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
Zika virus (ZIKV) is a flavivirus transmitted by Aedes mosquitos. Clinical symptoms include fever, rash, arthralgia, myalgia and conjunctivitis, but an estimated 80% of persons infected with ZIKV are asymptomatic [1]. In the acute phase, the clinical presentation is difficult to differentiate from other arbovirus infections such as DENV and chikungunya virus (CHIKV), which are transmitted by the same vectors and commonly co-circulate in the same geographic area. The course of ZIKV disease is usually mild and self-limiting, but further in-depth studies are needed to investigate if there is a causal link between ZIKV infecti...
Source: Journal of Clinical Virology - Category: Virology Authors: Tags: Case report Source Type: research
More News: Conjunctivitis | Epidemiology | Guillain-Barr Syndrome | Infectious Diseases | Outbreaks | Zika Virus