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Correspondence 23-valent pneumococcal polysaccharide vaccine against pneumococcal pneumonia

Motoi Suzuki and colleagues1 found that 23-valent pneumococcal polysaccharide vaccine (PPV23) showed low to moderate effectiveness against vaccine serotype pneumococcal pneumonia in Japanese people aged 65 years or older treated at four community-based hospitals from September, 2011, to August, 2014. As the authors wrote, 7-valent pneumococcal conjugate vaccine (PCV7) became commercially available for Japanese children in February, 2010, and it was incorporated into the routine immunisation schedule for children in April, 2013.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research

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Press releaseIndian Patent Office Delivers Major Blow to Affordable Pneumonia Vaccine HopesAugust 22, 2017Hopes for improved access to an affordable pneumococcal conjugate vaccine (PCV) that protects both children and adults from pneumonia was dealt a major blow after the Indian patent office granted a patent to the U.S. pharmaceutical corporation Pfizer.
Source: MSF News - Category: International Medicine & Public Health Authors: Source Type: news
Conclusion These refusal to vaccinate forms were created to increase vaccination rates, scare parents, and potentially take children away from parents who decline vaccines or mandate medical treatment. Parents should refuse to sign these forms. Has your child’s health care provider asked you to sign a refusal to vaccinate form? How did you respond? Please share your experiences in the comments section below. You can help other parents by sharing this article on social media. References: https://www.aap.org/en-us/Documents/immunization_refusaltovaccinate.pdf http://pediatrics.aappublications.org/content/115/5/1428.lo...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Missy Fluegge Top Picks Patricia Finn refusal form truth about vaccines vaccine refusal Source Type: blogs
Abstract We conducted a case-control study to elucidate associations between pneumonia in elderly individuals and 23-valent pneumococcal polysaccharide vaccine (PPSV23) and seasonal influenza vaccine (influenza vaccine). Here, we examined selection of controls in our study using an analytic epidemiology approach. The study period was from October 1, 2009 through September 30, 2014. Cases comprised ≥65-year-old patients newly diagnosed with pneumonia. For every case with pneumonia, two patients with other diseases (one respiratory medicine, one non-respiratory medicine) who were sex-, age-, visit date- and visit...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Authors: Abstract In the report "Pneumococcal Vaccination Among Medicare Beneficiaries Occurring After the Advisory Committee on Immunization Practices Recommendation for Routine Use Of 13-Valent Pneumococcal Conjugate Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine for Adults Aged ≥65 Years," on page 732, the second sentence of the discussion should have read "However, approximately 20%-25% of IPD cases and 10% of community-acquired pneumonia cases in adults aged ≥65 years are caused by PCV13 serotypes." PMID: 28817557 [PubMed - in process]
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Conclusion Because the mainstream media has financial interest in promoting vaccines, informed parents must seek information elsewhere about back to school vaccine mandates and exemptions. Parents, as you prepare to send your child back to school, do your homework and determine which exemptions are available in your area. A list of vaccine exemptions for all fifty states is published online by the National Vaccine Information Center. Sharing this article with other parents will also help them make informed decisions about vaccines. References: http://www.nvic.org/vaccine-laws/state-vaccine-requirements.aspx http://www.oma...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Top Stories truth about vaccines Vaccine Exemptions Source Type: blogs
Publication date: Available online 14 August 2017 Source:Journal of Global Antimicrobial Resistance Author(s): Paulina A. Hawkins, Patrick E. Akpaka, Michele Nurse-Lucas, Rebecca Gladstone, Stephen D. Bentley, Robert F. Breiman, Lesley McGee, William H. Swanston Introduction In Latin America and the Caribbean, pneumococcal infections were estimated to account for 12,000-18,000 deaths, 327,000 cases of pneumonia, 4,000 cases of meningitis and 1,229 cases of sepsis each year in children under five years old. Resistance of pneumococci to antimicrobial agents has evolved into a worldwide health problem in the last few decades...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
CONCLUSIONS: Our results confirm the immunogenic properties of PCV13 in former pneumococcal CAP patients including patients previously regarded as potential hyporesponders. A slightly diminished overall humoral response to polysaccharides characterizes the former pneumococcal CAP patients. ClinicalTrials.gov Identifier: NCT02141009. PMID: 28802755 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
We examined 458 strains of S. pneumoniae obtained from 22 pediatric institutions throughout Japan from January to June 2010 (immediately after the introduction of PCV‐7) and 370 strains obtained from 19 institutions from January to June 2012 (after PCV‐7 became widely used). The samples were collected from children aged 0–14 years with conditions such as respiratory tract infections (upper airway inflammation, bronchitis, and pneumonia), meningitis, and sepsis ResultsThe most frequent serotype in the 2010 strains was 19F (17.3%), followed by 6B (16.8%), and 23F (15.1%). The most frequent serotype in the 2012 stra...
Source: Pediatrics International - Category: Pediatrics Authors: Tags: Original Article Source Type: research
Publication date: Available online 2 August 2017 Source:Journal of Microbiological Methods Author(s): Rosemol Varghese, Ranjith Jayaraman, Balaji Veeraraghavan Streptococcus pneumoniae is a major cause of pneumonia, meningitis and other invasive diseases resulting in high mortality and morbidity among children under the age of five. Inaccurate identification of S. pneumoniae masks the exact estimation of disease burden and could delay treatment options. This is the common problem most frequently faced in developing countries due to several reasons that include poor infrastructure, insensitive operational procedures and la...
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
Abstract BACKGROUND: Many countries have observed an early and strong impact of implementation of the 13-valent pneumococcal conjugate vaccine (PCV13) on community-acquired pneumonia (CAP). High levels of C-reactive protein (CRP) and procalcitonin (PCT) are considered biomarkers of bacterial infection (particularly infection due to pneumococcus); therefore, PCV13 implementation should have different effectiveness on CAP depending on the levels of these two biomarkers. To demonstrate this assumption, we analyzed the evolution of number of CAP cases seen in pediatric emergency departments in France after PCV13 imple...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
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