Emerging Biomarkers of Illness Severity: Urinary Metabolites Associated with Sepsis and Necrotizing Methicillin ‐Resistant Staphylococcus aureus Pneumonia

ConclusionThese metabolic changes in the urine preceded the clinical severe sepsis phenotype, which suggests that detection of the extent of metabolic disruption can aid in the early identification of a sepsis phenotype in advance of clinical diagnosis. These data also support the utility of metabolomics for the development of clinical assays for the identification of patients with pediatric pneumonia at high risk for deterioration.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Special Issue on Precision Medicine Source Type: research