Age acts as an adverse independent variable for survival in acute lymphoblastic leukemia: Data from a cohort in Northeast Mexico

Conclusion Age plays a decisive role in clinical evolution of ALL and strongly influences outcome. Age over twenty represents a progressive high-risk factor for death. Teaser Acute lymphoblastic leukemia is a highly heterogeneous disease whose clinical course and outcome are strongly influenced by age. A cohort including 377 patients of all ages from a low-middle income and homogeneous population receiving standardized treatment protocols over a decade was analyzed. Age <1 and > 20 years was significantly associated with lower overall survival. Infants fared worst.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research