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Raleigh biopharma to go public through reverse merger

Raleigh-based Innovate Biopharmaceuticals is poised to become a public company through a reverse merger with Simi Valley, California-based Monster Digital (Nasdaq: MSDI). Innovate said Monday that it has entered into a nonbinding letter of intent with Monster Digital that would ultimately see Innovate trade on the Nasdaq exchange under a new ticker symbol. Innovate is developing a pipeline of drugs for the treatment of conditions, including celiac disease – an au toimmune disorder related to consuming…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news

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We report a case of sprue-like enteropathy associated with telmisartan. A 52-year-old man presented with chronic diarrhea, abdominal discomfort and significant weight loss. In the last 3 years, he had been treated with telmisartan 40 mg/day for hypertension after right adrenalectomy for an aldosterone-producing adenoma. Laboratory investigations showed no significant abnormalities: Hb 13.6 g/dL, serum albumin 3.9 g/dL, total cholesterol 193 mg/dL, serum creatinine 0.99 mg/dL, sodium 143.6 mmol/L, K(+) 4.3 mmol/L, calcium 9.3 mg/dL, phosphorus 3.9 mg/dL and 25-OH-D3 27.7 ng/mL. Duodenal histology showed subtotal VA and infl...
Source: Clin Med Res - Category: Research Authors: Tags: J Clin Med Res Source Type: research
ConclusionsGAD‐Alum as a subcutaneous prime and boost injection was safe in prediabetic young children but did not affect progression to type 1 diabetes. The safety of GAD‐Alum should prove useful in future prevention studies.
Source: Pediatric Diabetes - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conditions:   Capsule Endoscopy;   Inflammatory Bowel Diseases;   Celiac Disease Interventions:   Drug: Klean Prep;   Other: Clear liquids only Sponsors:   Sheffield Teaching Hospitals NHS Foundation Trust;   Hotel Dieu Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Removing disease-causing proteins from the grain could make it safe for celiacs to consume -- Read more on ScientificAmerican.com
Source: Scientific American - Category: Science Authors: Tags: Health The Sciences Biology Source Type: research
RHEUMATOID arthritis joint pain could by eased by cutting out gluten from your diet, as patients have an increased risk of developing coeliac disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
No abstract available
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Invited Commentary Source Type: research
Conclusions: Our study provided evidence of a high prevalence of CD among Saudi children (1.5%), a rate that is at least twice the average prevalence rate in Europe and North America.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research
BackgroundAntibodies against tissue transglutaminase (TTG) of isotype IgA (IgA‐aTTG) represent reliable diagnostic markers to confirm or exclude celiac disease (CD). Hemolysis (HL) is an important pre‐analytical factor. HL can be quantified as HL index (HI) correlating with the concentration of free hemoglobin. TTG is abundant in erythrocytes and released upon HL. In immunoassays, the released TTG may interfere with binding of IgA‐aTTG to the coated TTG. MethodsWe selected 17 HL‐free sera from children with biopsy‐confirmed CD: 7 with low‐positive (1‐5 multiples of upper limit of normal [×ULN]), 5 with ...
Source: Journal of Clinical Laboratory Analysis - Category: Laboratory Medicine Authors: Tags: RESEARCH ARTICLE Source Type: research
There are'striking'associations between celiac disease and other medical conditions, according to a large database study that suggests patients with unusual symptoms be screened.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
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