Raleigh biopharma to go public through reverse merger
Raleigh-based Innovate Biopharmaceuticals is poised to become a public company through a reverse merger with Simi Valley, California-based Monster Digital (Nasdaq: MSDI). Innovate said Monday that it has entered into a nonbinding letter of intent with Monster Digital that would ultimately see Innovate trade on the Nasdaq exchange under a new ticker symbol. Innovate is developing a pipeline of drugs for the treatment of conditions, including celiac disease – an au toimmune disorder related to consuming…
We report a case of sprue-like enteropathy associated with telmisartan. A 52-year-old man presented with chronic diarrhea, abdominal discomfort and significant weight loss. In the last 3 years, he had been treated with telmisartan 40 mg/day for hypertension after right adrenalectomy for an aldosterone-producing adenoma. Laboratory investigations showed no significant abnormalities: Hb 13.6 g/dL, serum albumin 3.9 g/dL, total cholesterol 193 mg/dL, serum creatinine 0.99 mg/dL, sodium 143.6 mmol/L, K(+) 4.3 mmol/L, calcium 9.3 mg/dL, phosphorus 3.9 mg/dL and 25-OH-D3 27.7 ng/mL. Duodenal histology showed subtotal VA and infl...
ConclusionsGAD‐Alum as a subcutaneous prime and boost injection was safe in prediabetic young children but did not affect progression to type 1 diabetes. The safety of GAD‐Alum should prove useful in future prevention studies.
Conditions: Capsule Endoscopy; Inflammatory Bowel Diseases; Celiac Disease Interventions: Drug: Klean Prep; Other: Clear liquids only Sponsors: Sheffield Teaching Hospitals NHS Foundation Trust; Hotel Dieu Hospital Not yet recruiting
Removing disease-causing proteins from the grain could make it safe for celiacs to consume -- Read more on ScientificAmerican.com
RHEUMATOID arthritis joint pain could by eased by cutting out gluten from your diet, as patients have an increased risk of developing coeliac disease.
No abstract available
Conclusions: Our study provided evidence of a high prevalence of CD among Saudi children (1.5%), a rate that is at least twice the average prevalence rate in Europe and North America.
BackgroundAntibodies against tissue transglutaminase (TTG) of isotype IgA (IgA‐aTTG) represent reliable diagnostic markers to confirm or exclude celiac disease (CD). Hemolysis (HL) is an important pre‐analytical factor. HL can be quantified as HL index (HI) correlating with the concentration of free hemoglobin. TTG is abundant in erythrocytes and released upon HL. In immunoassays, the released TTG may interfere with binding of IgA‐aTTG to the coated TTG. MethodsWe selected 17 HL‐free sera from children with biopsy‐confirmed CD: 7 with low‐positive (1‐5 multiples of upper limit of normal [×ULN]), 5 with ...
There are'striking'associations between celiac disease and other medical conditions, according to a large database study that suggests patients with unusual symptoms be screened.Medscape Medical News