Resolution of a Debilitating Paraneoplastic Parkinson-like Neurological Syndrome Following Tyrosine Inhibitor Therapy and Consolidative Nephrectomy in a Patient with Advanced Clear Cell Renal Cell  Carcinoma

Publication date: September 2017 Source:Urology Case Reports, Volume 14 Author(s): Naveed Ali, Alexander Kutikov, Daniel M. Geynisman Paraneoplastic syndromes are commonly encountered in renal cell carcinoma, but neurological manifestations are rare. Herein we report a case of a patient with locally advanced renal cell carcinoma who presented with Parkinson-like symptoms which prohibited surgery due to poor performance status. However, a significant improvement was noted after tyrosine kinase inhibitor therapy, allowing the patient to proceed to curative surgery.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research