Fosphenytoin-Induced Purple Glove Syndrome: A Case Report

Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1]. The characteristics of this syndrome occur in three different stages: appearance, progression, and resolution of symptoms. These characteristics usually occur in the upper extremity, distal to the intravenous access site.

Source: Clinical Neurology and Neurosurgery - June 19, 2017 Category: Neurosurgery Authors: Joseph W. Newman, Joseph R. Blunck, Ronald K. Fields, John E. Croom Tags: Case Report Source Type: research