State-Independent and Dependent Neural Responses to Psychosocial Stress in Current and Remitted Depression.

CONCLUSIONS: These findings provide novel evidence regarding the trait and state markers of depression on neural responses to psychosocial stress. Regional activation changes in the ventromedial prefrontal cortex and precuneus may reflect the trait markers of depression. Hyperactivation in the dorsolateral prefrontal cortex and striatum may represent a state-dependent compensatory mechanism during depression remission.
PMID: 28618857 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - June 16, 2017 Category: Psychiatry Authors: Ming Q, Zhong X, Zhang X, Pu W, Dong D, Jiang Y, Gao Y, Wang X, Detre JA, Yao S, Rao H Tags: Am J Psychiatry Source Type: research