Personal Health: Who Really Needs to Be Gluten-Free?
There are probably many people walking around with celiac disease who don ’ t know they have it.
Publication date: 10 November 2018Source: Sensors and Actuators B: Chemical, Volume 273Author(s): Marco Giannetto, Valentina Bianchi, Silvia Gentili, Simone Fortunati, Ilaria De Munari, Maria CareriAbstractA new compact diagnostic device exploiting the integration of screen printed electrode-based immunosensors and remote-controlled IoT-WiFi acquisition board has been realized and validated for diagnosis of Celiac Disease as case of study. The immunodevice is based on chemisorption of open tissue transglutaminase enzyme on the surface of gold nanoparticles-functionalized carbon screen printed electrodes. IgA and IgG anti-t...
A monoclonal antibody could help reduce symptoms of coeliac disease in people with the condition who are accidentally exposed to gluten, show study findings presented at Digestive Disease Week.
Myotonic dystrophy type 2 (DM2) is a dominantly inherited multisystem disorder caused by a CCTG repeat expansion in intron 1 of the CNBP gene on chromosome 3q21.3. DM2 is characterized by progressive proximal muscle weakness, myotonia, early-onset cataract, and multiorgan involvement including cardiac conduction abnormalities, gastrointestinal involvement and endocrine disturbances . Autoimmune diseases are more prevalent (21%) and autoantibodies are more frequently detected (25%) in patients with DM2 compared to patients with myotonic dystrophy type 1 and the general population .
In the first Wheat Belly book, I recounted the history of wheat from its wild-growing 14-chromosome einkorn ancestor, to the 28-chromosome emmer of Biblical times, to 42-chromosome spelt and other Triticum species, and finally to high-yield semi-dwarf strains created by agricultural scientists in the 1960s now comprises 99% of all wheat products sold. The quantity of additional changes introduced since are many, including selection of strains enriched in wheat germ agglutinin and phytates for their pest-resistant properties (while increasing human toxicity), gliadin and glutenin for desirable baking characteristics ...
Conclusions The diagnostic yield for EGDs is increased in patients with more specific symptoms (i. e. dysphagia, heartburn, HP, celiac disease). Consequently, as an invasive procedure, EGD warrants a strict indication. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Conclusions: Multiple symptoms and high serum anti-tTG antibody levels correlated with mucosal damage in children with CD. The role of immunohistochemical staining for intestinal anti-tTG mucosal deposits in the diagnosis of borderline CD is not yet established.Dig Dis
Molecular Genetics&Genomic Medicine, EarlyView.
Conclusion: Overall, the KIDSCREEN-52 questionnaire revealed that CD had no substantial negative impacts on the children ’s QOL. However, some concerns from the children’s perspective were identified, such as issues regarding relationships with their peers. These issues will need to be addressed in order to improve QOL in children with CD.What is Known:•According to the Spanish version of the specific CDDUX, parents and children felt CD had no substantial negative impacts on their HRQOL.What is New:•According to the generic KIDSCREEN-52 questionnaire, QOL in Spanish coeliac children does not seem to b...
ConclusionsOur review of quality improvement literature in gastroenterology revealed common themes of successful programs: Education was frequently used but often insufficient, the EMR may be underutilized in guiding decision making, and patient-reported outcomes were infrequently assessed. Further research may be needed to compare QI strategies directly.